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Misoprostol prior to hysteroscopy in premenopausal and post-menopausal women. A systematic review and meta-analysis
(2012)
Although several randomized controlled trials (RCTs) have examined the effect of misoprostol prior to hysteroscopy for cervical dilatation, no solid conclusion has been reached. We therefore set out to perform a meta-analysis ...
Publication bias in reproductive medicine: from the European Society of Human Reproduction and Embryology annual meeting to publication
(2011)
Background: Treatment decisions should ideally be based on well-designed randomized controlled trials (RCTs). Here we determine the rate of full publication of RCTs presented at annual meetings of the European Society of ...
Effects of leptin on the expression of fatty acid-binding proteins in human placental cell cultures
(2012)
The present study aimed to evaluate the protein expression of the transmembrane translocase FAT/CD36 and cytoplasmic H-FABP and L-FABP in human trophoblast tissue and evaluate the effects of exogenous leptin upon differential ...
Leptin in human reproduction
(1999)
The recent discovery of the obese (ob) gene has provided new insight into the mechanism which controls body fat mass. Leptin, a product of the ob gene, serves as the link between fat and the brain. This protein, by acting ...
Leptin concentrations in the follicular phase of spontaneous cycles and cycles superovulated with follicle stimulating hormone
(1998)
It has been reported that oestradiol may play a role in the production of leptin from adipocytes, To investigate this relationship further, nine normally ovulating women were studied during two menstrual cycles, i.e. an ...
Polycystic ovaries and obesity
(2015)
Almost 50% of the women with polycystic ovary syndrome (PCOS) are obese. Obesity in PCOS affects reproduction via various mechanisms. Hyperandrogenism, increased luteinizing hormone (LH) and insulin resistance play a pivotal ...
Oestradiol plus progesterone treatment increases serum leptin concentrations in normal women
(2001)
BACKGROUND: Previous studies have alluded to a role for both oestradiol and progesterone in the secretion of leptin from fat cells in the human, although direct evidence has yet to be obtained. The study aim was to assess ...
Mechanisms of follicular development: The role of gonadotrophins
(2008)
INTRODUCTION, Folliculogenesis in women is a dynamic and uninterrupted process from fetal life until menopause. Following pubertal maturation of the reproductive axis, all types of follicles from the primordial to the ...