Simulation to minimise patient self-inflicted lung injury: are we almost there?
Fecha
2022Language
en
Materia
Resumen
Computational modelling has been used to enlighten pathophysiological issues in patients with acute respiratory distress syndrome (ARDS) using a sophisticated, integrated cardiopulmonary model. COVID-19 ARDS is a pathophysiologically distinct entity characterised by dissociation between impairment in gas exchange and respiratory system mechanics, especially in the early stages of ARDS. Weaver and colleagues used computational modelling to elucidate factors contributing to generation of patient self-inflicted lung injury, and evaluated the effects of various spontaneous respiratory efforts with different oxygenation and ventilatory support modes. Their findings indicate that mechanical forces generated in the lung parenchyma are only counterbalanced when the respiratory support mode reduces the intensity of respiratory efforts. © 2022 British Journal of Anaesthesia
Colecciones
Ítems relacionados
Mostrando ítems relacionados por Título, autor o materia.
-
Early gastrostomy reduces the rate of ventilator-associated pneumonia in stroke or head injury patients
(2005)Presence of a nasogastric tube is a risk factor for the development of ventilator-associated pneumonia (VAP). Alternatively, gastrostomy can be used for administration of enteral feedings. To determine whether early ... -
Neuromuscular Blockade in the Pre- and COVID-19 ARDS Patients
(2022)Acute respiratory distress syndrome (ARDS) accounts for a quarter of mechanically ventilated patients, while during the pandemic, it overwhelmed the capacity of intensive care units (ICUs). Lung protective ventilation (low ... -
COVID-19 ARDS: Points to be considered in mechanical ventilation and weaning
(2021)The COVID-19 disease can cause hypoxemic respiratory failure due to ARDS, requiring invasive mechanical ventilation. Although early studies reported that COVID-19-associated ARDS has distinctive features from ARDS of other ...