Browsing by Subject "human"

The 12-in-1 procedure for the treatment of congenital idiopathic clubfoot

Dailiana, Z. H.; Beris, A. E.; Malizos, K. N.; Varitimidis, S. E.; Hantes, M.; Soucacos, P. N. (2008)

The purpose of this study was to assess the long-term results of an extended soft tissue release in a single procedure, for the treatment of congenital idiopathic clubfoot. Seventeen patients with 22 congenital idiopathic ...

4-Arylazo-3,5-diamino-1H-pyrazole CDK inhibitors: SAR study, crystal structure in complex with CDK2, selectivity, and cellular effects

Kryštof, V.; Cankař, P.; Fryšová, I.; Slouka, J.; Kontopidis, G.; Džubák, P.; Hajdúch, M.; Srovnal, J.; De Azevedo Jr, W. F.; Orság, M.; Paprskářová, M.; Rolčík, J.; Látr, A.; Fischer, P. M.; Strnad, M. (2006)

In a routine screening of our small-molecule compound collection we recently identified 4-arylazo-3,5-diamino-1H-pyrazoles as a novel group of ATP antagonists with moderate potency against CDK2-cyclin E. A preliminary SAR ...

The 5′ regulatory region of the human fetal globin genes is a gene conversion hotspot

Kalamaras, A.; Chassanidis, C.; Samara, M.; Chiotoglou, I.; Vamvakopoulos, N. K.; Papadakis, M. N.; Kollia, P.; Patrinos, G. P. (2008)

The human fetal globin genes consist of the first mammalian genomic loci for which gene conversion was reported. To date, 14 gene conversions have been described in the human Gγ- and Aγ-globin genes, the vast majority of ...

99mTc sestamibi as a prognostic factor of response to first-line therapy and outcome in patients with malignant lymphoma

Spyridonidis, T. J.; Matsouka, P.; Symeonidis, A.; Savvopoulos, C.; Vassilakos, P. J.; Apostolopoulos, D. J. (2013)

INTRODUCTION: Resistance to chemotherapy poses a major problem in cancer patients. Although of multifactorial origin, some of the implicated mechanisms also interfere with Tc-MIBI uptake and retention in cancer cells. The ...

Aberrant methylation of c-myc and c-fos protooncogenes and p53 tumor suppressor gene in myelodysplastic syndromes and acute non-lymphocytic leukemia

Papaggeli, P. C.; Kortsaris, A. C.; Matsouka, P. T. (2003)

Purpose: Aberrant methylation, as an epigenetic phenomenon, may precede and regulate the expression of genes involved in transformation mechanisms that lead to leukemogenesis of hemopoietic cells. The genes involved mostly ...

Abiotic and biotic factors affect efficacy of chlorfenapyr for control of stored-product insect pests

Kavallieratos, N. G.; Athanassiou, C. G.; Hatzikonstantinou, N.; Kavallieratou, H. N. (2011)

Laboratory bioassays were conducted to assess pyrole chlorfenapyr as a potential grain protectant against adults of Rhyzopertha dominica, Sitophilus oryzae, Prostephanus truncatus, Tribolium confusum, and Liposcelis ...

Accelerated hypofractionated radiotherapy schedules in breast cancer: A review of the current literature

Kalogeridi, M. A.; Kelekis, N.; Kouvaris, J.; Platoni, K.; Kyrias, G.; Pectasides, D.; Kouloulias, V. (2009)

Lumpectomy followed by breast irradiation is an alternative to mastectomy for patients with early-stage breast cancer. The purpose of radiation treatment following lumpectomy is to minimize the risk of recurrent cancer in ...

Accidental acute metabolic acidosis due to inappropriate selection of bicarbonate concentrate

Golphinopoulos, S.; Oustabasidou, N.; Liakopoulos, V.; Kiropoulos, T.; Stefanidis, I. (2005)

Haemodialysis using a bicarbonate concentrate (bicarbonate dialysis) is the treatment modality of choice for correction of metabolic acidosis in chronic renal failure. However, improper ratios of acid and bicarbonate ...

The accumulation of pleural fluid during labour

Gourgoulianis, K. I.; Karantanas, A. H.; Karvelas, S. N.; Molyvdas, P. A. (1997)

Objectives: Labour appears to promote the development of pleural effusion. The presence of pleural fluid at the end of normal pregnancy and after an uncomplicated labour was investigated using thoracic ultrasonography. ...

Actions for prevention and control of health threats related to maritime transport in European Union

Hadjichristodoulou, C.; Mouchtouri, V. A.; Guglielmetti, P.; Lemos, C. M.; Nichols, G.; Paux, T.; Schlaich, C.; Cornejo, M. D.; Martinez, C. V.; Dionisio, M.; Rehmet, S.; Jaremin, B.; Kremastinou, J. (2013)

Background: Actions at European Union level for International Health Regulations (IHR) 2005 implementation and maritime transport were focused on two European projects implemented between 2006 and 2011. Method: Situation ...

Acute phase markers for the differentiation of infectious and malignant pleural effusions

Kiropoulos, T. S.; Kostikas, K.; Oikonomidi, S.; Tsilioni, I.; Nikoulis, D.; Germenis, A.; Gourgoulianis, K. I. (2007)

Acute-phase markers, such as C-reactive protein (CRP), interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α), have been studied in inflammatory and malignant disorders. We examined the diagnostic value of these ...

Adenoid cystic carcinoma stage Ib1 treated with radical surgery displaying human papilloma virus 33 (HPV 33): immunoelectron microscopy and review

Daponte, A.; Grayson, W.; Moisuc, D.; Ebrahim, S.; Guidozzi, F. (2003)

BACKGROUND: The presence of human papilloma virus (HPV) 33 and possible myoepithelial differentiation in an adenoid cystic carcinoma of the cervix (ACC) Ib1 and the clinical outcome are reported. CASE: The case is an ACC, ...

Aiming at Tobacco Harm Reduction: A survey comparing smokers differing in readiness to quit

Loumakou, M.; Brouskeli, V.; Sarafidou, J. O. (2006)

Background: Greece has the highest smoking rates (in the 15-nation bloc) in Europe. The purpose of this study was to investigate Greek smokers' intention and appraisal of capability to quit employing the theoretical ...

Airborne algae and cyanobacteria: Occurrence and related health effects

Genitsaris, S.; Kormas, K. A.; Moustaka-Gouni, M. (2011)

Published information on airborne algae and cyanobacteria worldwide and the related human health effects is scarce. Since 1844, a total of 353 morphological taxa (genera or species) have been identified in aerobiological ...

Aldehyde dehydrogenase 1B1: Molecular cloning and characterization of a novel mitochondrial acetaldehyde-metabolizing enzyme

Stagos, D.; Chen, Y.; Brocker, C.; Donald, E.; Jackson, B. C.; Orlicky, D. J.; Thompson, D. C.; Vasiliou, V. (2010)

Ethanol-induced damage is largely attributed to its toxic metabolite, acetaldehyde. Clearance of acetaldehyde is achieved by its oxidation, primarily catalyzed by the mitochondrial class II aldehyde dehydrogenase (ALDH2). ...

Alpha-actinin: A multidisciplinary protein with important role in B-cell driven autoimmunity

Kikonomou, K. G.; Zachou, K.; Dalekos, G. N. (2011)

Alpha-actinin (α-actinin) is a ubiquitous cytoskeletal protein, which belongs to the superfamily of filamentous actin (F-actin) crosslinking proteins. It is present in multiple subcellular regions of both muscle and ...

Alpha-synuclein repeat variants and survival in parkinson's disease

Chung, S. J.; Biernacka, J. M.; Armasu, S. M.; Anderson, K.; Frigerio, R.; Aasly, J. O.; Annesi, G.; Bentivoglio, A. R.; Brighina, L.; Chartier-Harlin, M. C.; Goldwurm, S.; Hadjigeorgiou, G.; Jasinska-Myga, B.; Jeon, B. S.; Kim, Y. J.; Krüger, R.; Lesage, S.; Markopoulou, K.; Mellick, G.; Morrison, K. E.; Puschmann, A.; Tan, E. K.; Crosiers, D.; Theuns, J.; Van Broeckhoven, C.; Wirdefeldt, K.; Wszolek, Z. K.; Elbaz, A.; Maraganore, D. M.; Yahalom, G.; Orlev, Y.; Cohen, O. S.; Kozlova, E.; Friedman, E.; Inzelberg, R.; Hassin-Baer, S. (2014)

Objectives: To determine whether α-synuclein dinucleotide repeat (REP1) genotypes are associated with survival in Parkinson's disease (PD). Methods: Investigators from the Genetic Epidemiology of Parkinson's Disease ...