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Outcome of refractory to conventional and/or biologic treatment adult Still's disease following canakinumab treatment: Countrywide data in 50 patients

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Autor
Laskari K., Tektonidou P.M.G., Katsiari P.C., Athanassiou P., Dimopoulou D., Gerodimos C., Salamaliki C., Papagoras P.C., Settas P.L., Vassilopoulos P.D., Voulgari P.P.V., Zakalka M., Georgiadis A., Gkoni G., Daoussis P.D., Dimitroulas P.T., Iliou C., Kallitsakis I., Grika E.P., Mavragani P.C., Pikazis P.D., Raftakis J., Sarikoudis T., Kougkas N., Soukera D., Theodorou E., Tsatsani P., Tsiakou E., Vlachoyiannopoulos P.P., Vosvotekas G., Sfikakis P.P.P.
Fecha
2021
Language
en
DOI
10.1016/j.semarthrit.2020.10.011
Materia
abatacept
anakinra
canakinumab
corticosteroid
immunoglobulin
methotrexate
methylprednisolone
tocilizumab
tumor necrosis factor inhibitor
antirheumatic agent
biological product
canakinumab
monoclonal antibody
adolescent
adult
adult onset Still disease
aged
Article
clinical article
cohort analysis
disease activity
disease resistance
drug dose intensification
drug efficacy
drug megadose
drug safety
drug withdrawal
female
follow up
genital tract infection
human
leukopenia
longitudinal study
macrophage activation syndrome
male
monotherapy
mouth infection
multicenter study
onset age
pneumonia
priority journal
relapse
remission
respiratory tract infection
retrospective study
skin infection
soft tissue infection
treatment outcome
treatment response
urinary tract infection
clinical trial
off label drug use
treatment outcome
Adult
Antibodies, Monoclonal, Humanized
Antirheumatic Agents
Biological Products
Humans
Off-Label Use
Retrospective Studies
Still's Disease, Adult-Onset
Treatment Outcome
W.B. Saunders
Mostrar el registro completo del ítem
Resumen
Objective: To assess the efficacy and safety of the IL-1b inhibitor canakinumab in all adults with refractory Still's disease identified from the National Organization For Medicines for off-label drug use. Methods
URI
http://hdl.handle.net/11615/75698
Colecciones
  • Δημοσιεύσεις σε περιοδικά, συνέδρια, κεφάλαια βιβλίων κλπ. [19735]

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