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Left atrial remodelling contributes to the progression of asymptomatic left ventricular systolic dysfunction to chronic symptomatic heart failure
(2008)
Systolic heart failure (HF) is a progressive disorder that often begins with asymptomatic left ventricular (LV) systolic dysfunction and culminates in symptoms from fluid overload and poor end-organ perfusion. The progression ...
Efficacy and safety of high dose versus low dose furosemide with or without dopamine infusion: The Dopamine in Acute Decompensated Heart Failure II (DAD-HF II) Trial
(2014)
Aims: The role of low-dose dopamine infusion in patients with acute decompensated heart failure (ADHF) remains controversial. We aim to evaluate the efficacy and safety of high-versus low-dose furosemide with or without ...
Hospitalization Epidemic in Patients With Heart Failure: Risk Factors, Risk Prediction, Knowledge Gaps, and Future Directions
(2011)
Patients with heart failure (HF) are hospitalized over a million times annually in the United States. Hospitalization marks a fundamental change in the natural history of HF, leading to frequent subsequent rehospitalizations ...
Lessons learnt from the autopsies of 445 cases of sudden cardiac death in adults
(2005)
Aim To determine the cause of sudden cardiac death in adults who underwent autopsy. Methods Four hundred and forty-five sudden cardiac deaths occurred within 1 h of the symptoms onset, and all other cardiac and noncardiac ...
Carotid plaque composition in stable and unstable coronary artery disease
(2005)
Background Several pieces of evidence suggest that formation of complex atheromatous plaques may be influenced not only by local but also by systemic factors. Methods Twenty-five patients (16 men/9 women, age 63 +/- 10 ...
Long-term prognostic value of heart-rate recovery after treadmill testing in patients with diabetes mellitus
(2009)
Background: Heart-rate recovery (HRR) is considered to be an independent predictor of cardiac and all-cause mortality. We examined the long-term prognostic value of HRR in patients suffering from diabetes mellitus. Methods: ...
Postoperative stroke in cardiac surgery is related to the location and extent of atherosclerotic disease in the ascending aorta
(2001)
OBJECTIVES The aim of the study was to evaluate the risk from calcified atheromas in the ascending aorta, and the extent and topography of the disease in the development of stroke after cardiac surgery. BACKGROUND Postoperative ...
Ranolazine enhances nicardipine-induced relaxation of alpha1-adrenoceptor-mediated contraction on isolated rabbit aorta
(2015)
Ranolazine (RAN) and nicardipine (NIC) have been studied for their vasorelaxing effects but the combination of these agents against adrenergic vasoconstriction has not been tested. The present study aimed at investigating ...