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Left atrial remodelling contributes to the progression of asymptomatic left ventricular systolic dysfunction to chronic symptomatic heart failure
(2008)
Systolic heart failure (HF) is a progressive disorder that often begins with asymptomatic left ventricular (LV) systolic dysfunction and culminates in symptoms from fluid overload and poor end-organ perfusion. The progression ...
Lessons learnt from the autopsies of 445 cases of sudden cardiac death in adults
(2005)
Aim To determine the cause of sudden cardiac death in adults who underwent autopsy. Methods Four hundred and forty-five sudden cardiac deaths occurred within 1 h of the symptoms onset, and all other cardiac and noncardiac ...
Carotid plaque composition in stable and unstable coronary artery disease
(2005)
Background Several pieces of evidence suggest that formation of complex atheromatous plaques may be influenced not only by local but also by systemic factors. Methods Twenty-five patients (16 men/9 women, age 63 +/- 10 ...
Long-term prognostic value of heart-rate recovery after treadmill testing in patients with diabetes mellitus
(2009)
Background: Heart-rate recovery (HRR) is considered to be an independent predictor of cardiac and all-cause mortality. We examined the long-term prognostic value of HRR in patients suffering from diabetes mellitus. Methods: ...
Postoperative stroke in cardiac surgery is related to the location and extent of atherosclerotic disease in the ascending aorta
(2001)
OBJECTIVES The aim of the study was to evaluate the risk from calcified atheromas in the ascending aorta, and the extent and topography of the disease in the development of stroke after cardiac surgery. BACKGROUND Postoperative ...
Dose-Related Shortening of Ventricular Tachycardia Cycle Length After Administration of the K-ATP Channel Opener Bimakalim in a 4-Day-Old Chronic Infarct Anesthetized Pig Model
(2009)
Potassium channel openers are known to act on potassium ATP-dependent channels in cardiac tissue. Such agents may exacerbate acceleration of acute ischemia-induced ventricular repolarization and aggravate arrhythmias. To ...
Assessment of local atrial repolarization in a porcine acetylcholine model of atrial flutter and fibrillation
(2009)
Objectives - Progressive electrical alternans followed by conduction block and fibrillatory conduction have been suggested to precede disorganization of atrial flutter (Afl) to atrial fibrillation (AF). The purpose of the ...
Pneumopericardium after blunt chest trauma: Mechanical ventilation with positive pressure must be avoided
(2008)
A 38-year-old polytraumatized man was admitted with signs of cardiogenic shock (low blood pressure, tachycardia, tachypnea, and elevated central venous pressure). A near tension pneumopericardium was revealed by thorax CT. ...
Cytokine levels in the sera of patients with idiopathic pulmonary fibrosis
(2006)
Background: Idiopathic pulmonary fibrosis (IPF) is a fibroprotiferative disorder. Cytokines contribute an important but yet undefined role to its pathogenesis. Objectives: The present study aims to compare serum levels of ...
Obstructive steep-disordered breathing and plasma levels of vascular endothelial growth factor in children
(2006)
Vascular endothelial growth factor (VEGF) may be one of the pathophysiologic links in the association between obstructive steep apnea-hypopnea and cardiovascular disease. Morning serum VEGF levels are increased in children ...