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Transduodenal sphincteroplasty and transampullary septectomy for sphincter of Oddi dysfunction
(2002)
Background: The diagnosis and management of sphincter of Oddi dysfunction are controversial issues. Both surgical and endoscopic series report modest success in the treatment of this condition. There is evidence from ...
Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: A systems biology based approach
(2010)
To identify novel genes and pathways associated with AMD, we performed microarray gene expression and linkage analysis which implicated the candidate gene, retinoic acid receptor-related orphan receptor alpha (RORA, 15q). ...
Noninvasive histologic grading of solid astrocytomas using proton magnetic resonance spectroscopy
(2004)
Background: Proton magnetic resonance spectroscopy (1H MRS) constitutes a promising modality to assess intracranial pathology. We present our experience using this method in grading solid brain astrocytomas. Material and ...
Transferrin receptor-1 and 2 expression in chronic lymphocytic leukemia
(2006)
Transferrin receptor (TfR)-1 and 2 mRNA and CD71 (TfR1) expression was analyzed in 118 CLL patients. Ninety-five out of 109 analyzed cases expressed CD71, mostly at a high level; 60% of CD71 (+) cases were IGH-mutated. All ...
Immunoglobulin D myeloma: Clinical features and outcome in the era of novel agents
(2014)
Objectives: Immunoglobulin D (IgD) multiple myeloma is an uncommon variant of the disease probably associated with poorer prognosis. However, data on IgD myeloma patients treated in the novel agent era are lacking. Methods: ...
In vivo evaluation of CUP1A2 and CYP2A6 activities in a Greek population during menopause
(2008)
Human CYP enzyme system is involved in the metabolism of various endogenous compounds. Previous studies have shown that CYP activity is influenced by age and gender. In the present study caffeine metabolites were used for ...
Prevalence of sleep-related symptoms in a primary care population - Their relation to asthma and COPD
(2007)
Aims: The aim of this study was to clarify the association between obstructive sleep apnoea/hypopnoea syndrome (OSAHS)-related symptoms and physician-diagnosed asthma and COPD. Methods: 1501 subjects aged 19-90 years ...
Loss of heterozygosity in DNA mismatch repair genes in human atherosclerotic plaques
(2001)
To detect the incidence of loss of heterozygosity (LOH) in DNA mismatch repair genes (MMR) occurring in atherosclerosis, fifty human autopsy cases of atherosclerosis were examined for LOH using 19 microsatellite markers, ...
Validation of the Augmentation Severity Rating Scale (ASRS): A multicentric, prospective study with levodopa on restless legs syndrome
(2007)
Background: Augmentation is the main complication during long-term dopaminergic treatment of restless legs syndrome (RLS) and reflects an overall increase in RLS severity. Its severity varies considerably from a minor ...
Alpha-synuclein repeat variants and survival in parkinson's disease
(2014)
Objectives: To determine whether α-synuclein dinucleotide repeat (REP1) genotypes are associated with survival in Parkinson's disease (PD). Methods: Investigators from the Genetic Epidemiology of Parkinson's Disease ...