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  •   University of Thessaly Institutional Repository
  • Επιστημονικές Δημοσιεύσεις Μελών ΠΘ (ΕΔΠΘ)
  • Δημοσιεύσεις σε περιοδικά, συνέδρια, κεφάλαια βιβλίων κλπ.
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  •   University of Thessaly Institutional Repository
  • Επιστημονικές Δημοσιεύσεις Μελών ΠΘ (ΕΔΠΘ)
  • Δημοσιεύσεις σε περιοδικά, συνέδρια, κεφάλαια βιβλίων κλπ.
  • View Item
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Genesis 1 posterior cruciate-retaining total knee arthroplasty with asymmetric tibial tray: An 18-to-26-year long-term clinical outcome study

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Author
Georgaklis V.A., Karachalios T., Makridis K.G., Badras S.L., Palaiochorlidis I.S., Malizos K.N., Badras L.S.
Date
2019
Language
en
DOI
10.1016/j.knee.2019.04.014
Keyword
polyethylene
adult
aged
Article
clinical outcome
cohort analysis
controlled study
deep vein thrombosis
female
follow up
human
Kaplan Meier method
knee function
knee osteoarthritis
Knee Society Score
major clinical study
male
Oxford Knee Score
priority journal
prospective study
prosthesis loosening
range of motion
revision arthroplasty
total knee arthroplasty
wound healing impairment
knee prosthesis
knee replacement
middle aged
prosthesis complication
prosthesis design
reoperation
very elderly
Aged
Aged, 80 and over
Arthroplasty, Replacement, Knee
Female
Follow-Up Studies
Humans
Knee Prosthesis
Male
Middle Aged
Polyethylene
Prospective Studies
Prosthesis Design
Prosthesis Failure
Reoperation
Elsevier B.V.
Metadata display
Abstract
Background: To present the long-term clinical and radiological outcomes of the Genesis I posterior cruciate-retaining total knee arthroplasty (TKA) (Smith & Nephew Orthopaedics, Memphis, TN, USA) (one of the first designed with an asymmetric tibial tray). Methods: Prospectively collected data from 117 cemented TKAs performed on 95 patients were evaluated using this design, with a mean follow-up of 21.5 years (range, 18–26). Failures, complication rates, and clinical (both subjective and objective) and radiological outcomes were assessed for all patients. Results: Seven failures occurred (wear and structural failure of the polyethylene insert) and six revision surgeries were performed at a mean of 10 years (range, three to 14) from the index operation. No revision of either the femoral or tibial components for aseptic loosening was performed. Survivorship analysis showed a cumulative success rate of 93.53% (95% CI, 92.75–94.32%) at 20 and 25 years, with revision for any reason as an end point. All patients showed a statistically significant improvement (P = 0.001) in the Knee Society and Oxford knee rating scores. Conclusions: This study demonstrated satisfactory long-term clinical outcomes for this TKA design, with revisions being related to polyethylene wear structural failure. © 2019 Elsevier B.V.
URI
http://hdl.handle.net/11615/72055
Collections
  • Δημοσιεύσεις σε περιοδικά, συνέδρια, κεφάλαια βιβλίων κλπ. [19735]

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