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  •   University of Thessaly Institutional Repository
  • Επιστημονικές Δημοσιεύσεις Μελών ΠΘ (ΕΔΠΘ)
  • Δημοσιεύσεις σε περιοδικά, συνέδρια, κεφάλαια βιβλίων κλπ.
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  •   University of Thessaly Institutional Repository
  • Επιστημονικές Δημοσιεύσεις Μελών ΠΘ (ΕΔΠΘ)
  • Δημοσιεύσεις σε περιοδικά, συνέδρια, κεφάλαια βιβλίων κλπ.
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External validation of the ASTRAL score to predict 3-and 12-month functional outcome in the china national stroke registry

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Author
Liu, G.; Ntaios, G.; Zheng, H.; Wang, Y.; Michel, P.; Wang, D. Z.; Fang, J.; Papavasileiou, V.; Liu, L.; Dong, K.; Wang, C.; Zhao, X.
Date
2013
DOI
10.1161/STROKEAHA.113.000993
Keyword
ASTRAL score
China National Stroke Registry
acute stroke registry and analysis of lausanne
aged
article
brain ischemia
cerebrovascular accident
China
correlation coefficient
disease registry
female
human
major clinical study
male
named inventories, questionnaires and rating scales
outcome assessment
prediction
priority journal
prognosis
prospective study
Rankin scale
scoring system
Aged, 80 and over
Asian Continental Ancestry Group
Follow-Up Studies
Humans
Middle Aged
Registries
Risk Factors
Severity of Illness Index
Stroke
Time Factors
Treatment Outcome
Metadata display
Abstract
BACKGROUND AND PURPOSE-: The ASTRAL score was recently introduced as a prognostic tool for acute ischemic stroke. It predicts 3-month outcome reliably in both the derivation and the validation European cohorts. We aimed to validate the ASTRAL score in a Chinese stroke population and moreover to explore its prognostic value to predict 12-month outcome. METHODS-: We applied the ASTRAL score to acute ischemic stroke patients admitted to 132 study sites of the China National Stroke Registry. Unfavorable outcome was assessed as a modified Rankin Scale score >2 at 3 and 12 months. Areas under the curve were calculated to quantify the prognostic value. Calibration was assessed by comparing predicted and observed probability of unfavorable outcome using Pearson correlation coefficient. RESULTS-: Among 3755 patients, 1473 (39.7%) had 3-month unfavorable outcome. Areas under the curve for 3 and 12 months were 0.82 and 0.81, respectively. There was high correlation between observed and expected probability of unfavorable 3-and 12-month outcome (Pearson correlation coefficient: 0.964 and 0.963, respectively). CONCLUSIONS-: ASTRAL score is a reliable tool to predict unfavorable outcome at 3 and 12 months after acute ischemic stroke in the Chinese population. It is a useful tool that can be readily applied in clinical practice to risk-stratify acute stroke patients. © 2013 American Heart Association, Inc.
URI
http://hdl.handle.net/11615/30376
Collections
  • Δημοσιεύσεις σε περιοδικά, συνέδρια, κεφάλαια βιβλίων κλπ. [19672]

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Η δικτυακή πύλη της Ευρωπαϊκής Ένωσης
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