DNA damage and repair in obstructive sleep apnea syndrome

Abstract

The Obstructive Sleep Apnea is a respiratory disorder characterized by short breathing pauses during sleep. These pauses vary according to the Apnea type and the severity of the case. People suffering from Obstructive Sleep Apnea are in increased danger of developing heart disease, strong headaches, restless sleep and difficulties in driving and working. No study has yet been performed on the lymphocytes DNA damage and repair sensitivity of Apnea suffering people, while experiments on lymphocytes and neurocytes under hypoxia and/or anoxia already contacted have shown DNA damage. These results could be correlated to data from Apnea Syndrome since lymphocytes from both groups are not oxygenated properly.