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Inhibitory Effect of Submaximal Doses of Ghrelin on Gonadotropin Secretion in Women
(2014)
The effect of ghrelin on gonadotropin secretion has been equivocal. Recent data have shown an inhibitory effect of repeated injections of ghrelin on nocturnal LH and FSH secretion in women. The aim of this study was to ...
Changes in gonadotrophin response to gonadotrophin releasing hormone in normal women following bilateral ovariectomy
(1997)
OBJECTIVE Pituitary responsiveness to GnRH varies throughout the normal menstrual cycle, We have investigated whether there are differences in the ovarian mechanisms which regulate gonadotrophin secretion between the ...
Leptin concentrations in the follicular phase of spontaneous cycles and cycles superovulated with follicle stimulating hormone
(1998)
It has been reported that oestradiol may play a role in the production of leptin from adipocytes, To investigate this relationship further, nine normally ovulating women were studied during two menstrual cycles, i.e. an ...
Inhibin secretion in women with the polycystic ovary syndrome before and after treatment with progesterone
(2011)
Objectives: It has been suggested that inhibin secretion is altered in women with the polycystic ovary syndrome (PCOS). However, the contribution of a preceding luteal phase has not been taken into account. The aim of the ...
Ovarian control of pituitary sensitivity of luteinizing hormone secretion to gonadotropin-releasing hormone in women with the polycystic ovary syndrome
(2009)
This study investigated the ovarian control of LH responsiveness to GnRH in anovulatory women with the polycystic ovary syndrome (PCOS). It is suggested that the enhanced pituitary sensitivity of LH secretion to GnRH in ...
The endocrine effects of multiple folliculogenesis
(2011)
Induction of multiple follicular development is a common practice in IVF programmes. Nevertheless, such an approach is not without implications. Apart from the high multiple pregnancy rate, marked changes in the secretion ...
Changes in pituitary sensitivity to GnRH in estrogen-treated post-menopausal women: evidence that gonadotrophin surge attenuating factor plays a physiological role
(2004)
BACKGROUND: The purpose of this study was to investigate changes in pituitary response to GnRH in post-menopausal women during substitution treatment with exogenous estrogen and progesterone. METHODS: Seven healthy ...
FSH modulatory effect on human granulosa cells: a gene-protein candidate for gonadotrophin surge-attenuating factor
(2011)
Previous evidence indicates a homology of gonadotrophin surge-attenuating factor (GnSAF) to the carboxyl terminal of human serum albumin (HSA) and the ability of human granulosa cells to produce mRNA transcripts corresponding ...
Ovarian feedback, mechanism of action and possible clinical implications
(2006)
The secretion of gonadotrophins from the pituitary in women is under ovarian control via negative and positive feedback mechanisms. Steroidal and non-steroidal substances mediate the ovarian effects on the hypothalamic-pituitary ...
The role of gonadotropins in the follicular phase
(2010)
Folliculogenesis in humans is a lengthy process that involves several regulators. Pituitary gonadotropins play crucial roles in the late stages, particularly in the last 15 days of follicle maturation. During the intercycle ...