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Global assessment of the COPD patient: Time to look beyond FEV1?
(2009)
COPD is a diverse disease entity with multiple dimensions that uniquely define the patient's performance, morbidity and mortality. FEV1 is both the traditional metric used to define the progression of COPD as well as the ...
COPD prevalence and the differences between newly and previously diagnosed COPD patients in a spirometry program
(2010)
Aims: To evaluate the prevalence and severity of COPD in a primary care population participating in a spirometry program. Differences between newly and previously diagnosed COPD patients were identified. Methods: A spirometry ...
Predicting Short-term Mortality in Patients With Pulmonary Embolism: A Simple Model
(2013)
Background: The aim of the present study was to develop a simple prognostic rule that could classify patients with pulmonary embolism (PE) into categories of increased risk of 30-day mortality. Methods: One hundred patients ...
The Association of Metabolic Syndrome with Adipose Tissue Hormones and Insulin Resistance in Patients with COPD without Co-morbidities
(2011)
Chronic obstructive pulmonary disease (COPD) and metabolic syndrome represent common causes of morbidity and mortality in ageing populations. The effect of the co-existence of COPD and metabolic syndrome on adipose tissue ...
Associations between BODE Index and Systemic Inflammatory Biomarkers in COPD
(2011)
Background: COPD is a multicomponent disease and systemic inflammation represents one of the possible mechanisms responsible for its systemic manifestations, including skeletal muscle weakness and cachexia. Fat-free mass ...
Systemic and airway inflammation and the presence of emphysema in patients with COPD
(2010)
The aim of this study was to determine the impact of HRCT-confirmed emphysema on biomarkers evaluating airway and systemic inflammation in COPD patients. Forty-nine consecutive male COPD outpatients with stable COPD were ...
Serum VEGF levels are related to the presence of pulmonary arterial hypertension in systemic sclerosis
(2009)
Background: The association between systemic sclerosis and pulmonary arterial hypertension (PAH) is well recognized. Vascular endothelial growth factor (VEGF) has been reported to play an important role in pulmonary ...
Secondhand smoke exposure induces acutely airway acidification and oxidative stress
(2013)
Previous studies have shown that secondhand smoke induces lung function impairment and increases proinflammatory cytokines. The aim of the present study was to evaluate the acute effects of secondhand smoke on airway ...
Exhaled breath condensate pH as a biomarker of COPD severity in ex-smokers
(2011)
Endogenous airway acidification, as assessed by exhaled breath condensate (EBC) pH, is present in patients with stable COPD. The aim of this study was to measure EBC pH levels in a large cohort of COPD patients and to ...