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Pus1p-dependent tRNA Pseudouridinylation Becomes Essential When tRNA Biogenesis Is Compromised in Yeast
(2001)
Yeast Pus1p catalyzes the formation of pseudouridine (ψ) at specific sites of several tRNAs, but its function is not essential for cell viability. We show here that Pus1p becomes essential when another tRNA: pseudouridine ...
Bone marrow side population cells are enriched for progenitors capable of myogenic differentiation
(2008)
Although the contribution of bone marrow-derived cells to regenerating skeletal muscle has been repeatedly documented, there remains considerable debate as to whether this incorporation is exclusively a result of inflammatory ...
Pleural electrophysiology variations according to location in pleural cavity
(2009)
The aim of the study was to compare the electrophysiology profile of sheep pleura originated from different locations of the pleural cavity with the respective profile in humans. Sheep specimens obtained from upper and ...
Biophysical characterization of V3-lipopeptide liposomes influencing HIV-1 infectivity
(2007)
The V3-loop of the HIV-1 gp120 alters host cell immune function and modulates infectivity. We investigated biophysical parameters of liposome constructs with embedded lipopeptides from the principle neutralizing domain of ...
Intrafamilial spread of hepatitis B virus infection in Greece
(2005)
Objective: No study has investigated the intrafamilial spread of hepatitis B virus (HBV) in Greece. We conducted a 9-year prospective study to determine the rate of HBV spread in family members when a member is identified ...
Enhancement of the transmesothelial resistance of the parietal sheep peritoneum by epinephrine in vitro: Ussing-type chamber experiments
(2005)
The peritoneal mesothelium constitutes an ion transport barrier that is taken advantage of in peritoneal dialysis. The aim of this study was to investigate the effects of epinephrine on the electrical transmesothelial ...
Rapid effects of 17β-estradiol and progesterone on sheep visceral and parietal pleurae via a nitric oxide pathway
(2002)
We investigated the effects of 17β-estradiol and progesterone on transepithelial electrical resistance (R TE) in sheep visceral and parietal pleurae. Specimens of intact pleurae from adult female sheep were used. The samples ...
Detection of unusual mutation within the VP1 region of different re-isolates of poliovirus Sabin vaccine
(2006)
In the present study, a genomic analysis of full VP1 sequence region of 15 clinical re-isolates (14 healthy vaccinees and one bone marrow tumor patient) was conducted, aiming to the identification of mutations and to the ...
Genetic growth potential interacts with nutrition on the ability of mice to cope with Heligmosomoides bakeri infection
(2009)
Artificial selection for improved productivity may reduce an animal's ability to cope with pathogens. Here, we used Roslin mice, uniquely divergently selected for high (ROH) and low (ROL) body weight, to assess interactive ...
Minimally invasive and selective hydrodynamic gene therapy of liver segments in the pig and human
(2008)
This paper highlights our experience of the transfer of hydrodynamic gene therapy (HGT) from the large animal, the pig, into clinical practice. The modification of balloon catheters and the development of a minimally ...