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Arginase type I as a marker of coronary heart disease in hemodialysis patients
(2011)
Cardiovascular disease, and mainly coronary heart disease (CHD), is the leading cause of death in hemodialysis (HD) patients. Non-traditional risk factors may play an important role in this population. Arginase is known ...
Indoleamine 2,3-dioxygenase is increased in hemodialysis patients and affects immune response to hepatitis B vaccination
(2011)
Background: Acquired immunity is impaired in hemodialysis (HD) patients. Indoleamine 2,3-dioxygenase (IDO) is inducible by inflammation and through tryptophan depletion and generation of kynurenine pathway products suppresses ...
Serum osteoprotegerin is markedly increased and may contribute to decreased blood T cell count in hemodialysis patients
(2013)
Acquired immunity is impaired in hemodialysis (HD) patients, and decreased T cell number may contribute. Receptor activator of nuclear factor-kappa B ligand (RANKL) and osteoprotegerin (OPG) are expressed in cells of the ...
Damage-associated molecular patterns derived from mitochondria may contribute to the hemodialysis-associated inflammation
(2014)
Inflammation is common in hemodialysis (HD) patients. Mitochondrial damage-associated molecular patterns (DAMPs) are released during cell necrosis or apoptosis and induce inflammation. Cell apoptosis is increased in HD ...