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Mostrando ítems 61-70 de 105
Primary biliary cirrhosis and Henoch-Schonlein purpura: report of two cases and review of the literature
(2007)
We describe, for the first time, two adult patients with primary biliary cirrhosis (PBC) who presented palpable purpuric lesions on the lower extremities and buttocks. Skin biopsy was consistent with Henoch-Schonlein purpura ...
Primary biliary cirrhosis associated with systemic sclerosis: Diagnostic and clinical challenges
(2011)
Patients with primary biliary cirrhosis (PBC) often have concurrent limited systemic sclerosis (SSc). Conversely, up to one-fourth of SSc patients are positive for PBC-specific antimitochondrial antibodies (AMA). The ...
Role of immunohistochemistry for hepatitis D and hepatitis B virus in hepatitis delta
(2014)
Background & Aims: Immunohistochemical assessment of liver tissue in chronic delta hepatitis (CDH) is underinvestigated. Aim of the study was (i) to assess variables associated with hepatitis D antigen (HDAg), hepatitis B ...
Human peripheral blood mononuclear cell culture for flow cytometric analysis of phosphorylated mitogen-activated protein kinases
(2012)
Lymphocyte activation and fine tuning of downstream signaling circuits for the regulation of cytokine expression are critical for a successful immune response. Hence, technical protocols permitting simultaneous testing of ...
Prospective evaluation of PBC-specific health-related quality of life questionnaires in patients with primary sclerosing cholangitis
(2015)
Background & Aims: Primary biliary cirrhosis and Primary sclerosing cholangitis are autoimmune cholestatic liver diseases sharing a lot in common, including a significant impairment of patients' health-related quality of ...
Lamivudine plus interleukin-12 combination therapy in chronic hepatitis B: Antiviral and immunological activity
(2005)
Interleukin-12 (IL-12) is an immunomodulatory cytokine that promotes cellular immunity. Pre-clinical data suggest that IL-12 inhibits hepatitis B virus (HBV) replication by stimulating interferon-gamma (IFN-γ) production. ...