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Inhibitor-based methods for the detection of KPC carbapenemase-producing Enterobacteriaceae in clinical practice by using boronic acid compounds

Pournaras, S.; Poulou, A.; Tsakris, A. (2010)

Enterobacteriaceae clinical strains that produce the class A carbapenem-hydrolysing enzyme KPC (Klebsiella pneumoniae carbapenemase) are increasingly reported worldwide, and are already endemic in North and South America, ...

Differential fungicidal activities of amphotericin B and voriconazole against Aspergillus species determined by microbroth methodology

Meletiadis, J.; Antachopoulos, C.; Stergiopoulou, T.; Pournaras, S.; Roilides, E.; Walsh, T. J. (2007)

Antifungal agents may differ in their fungicidal activities against Aspergillus spp. In order to compare the fungicidal activities of voriconazole and amphotericin B against 40 isolates of Aspergillus fumigatus, A. flavus, ...

Intensive care unit dissemination of multiple clones of linezolid-resistant Enterococcus faecalis and Enterococcus faecium

Ntokou, E.; Stathopoulos, C.; Kristo, I.; Dimitroulia, E.; Labrou, M.; Vasdeki, A.; Makris, D.; Zakynthinos, E.; Tsakris, A.; Pournaras, S. (2012)

Outbreaks caused by linezolid-resistant (LR) enterococci remain rare. We report the epidemiological and molecular characteristics of the multiclonal dissemination of LR enterococci in the intensive care unit (ICU) of a ...

Identification of multi-resistant strains of Acinetobacter baumannii from an ICU in Greece using sequence-based typing and PFGE

Trikaliotis, C.; Gogou, V.; Pournaras, S.; Tsorlini, H.; Katsifa, H.; Ramantani, E.; Arvanitidou, M. (2011)

Acinetobacter baumannii has emerged as an important nosocomial pathogen in many European countries, including Greece. In this study, we analysed 20 multi-resistant A. baumannii strains, derived from the First intensive ...

Global evolution of multidrug-resistant Acinetobacter baumannii clonal lineages

Zarrilli, R.; Pournaras, S.; Giannouli, M.; Tsakris, A. (2013)

The rapid expansion of Acinetobacter baumannii clinical isolates exhibiting resistance to carbapenems and most or all available antibiotics during the last decade is a worrying evolution. The apparent predominance of a few ...

Alterations of Deadenylase Expression in Acute Leukemias: Evidence for Poly(A)-Specific Ribonuclease as a Potential Biomarker

Maragozidis, P.; Karangeli, M.; Labrou, M.; Dimoulou, G.; Papaspyrou, K.; Salataj, E.; Pournaras, S.; Matsouka, P.; Gourgoulianis, K. I.; Balatsos, N. A. A. (2012)

Background/Aims: The degradation of mRNA is a key process in the control of gene expression correlated to anomalous cell proliferation. The rate-limiting step of mRNA degradation is the removal of the poly(A) tail by ...

Characterization of In3Mor, a new integron carrying VIM-1 metallo-beta-lactamase and sat1 gene, from Morganella morganii

Tsakris, A.; Ikonomidis, A.; Spanakis, N.; Poulou, A.; Pournaras, S. (2007)

Objectives: A carbapenem-resistant Morganella morganii clinical isolate that was phenotypically metallo-beta-lactamase (MBL)-positive was recovered from a Greek patient. The aim of the study was to analyse the structure ...

Identification of a novel bla(OXA-51) variant, bla(OXA-92), from a clinical isolate of Acinetobacter baumannii

Tsakris, A.; Ikonomidis, A.; Spanakis, N.; Pournaras, S.; Bethimouti, K. (2007)

Spread of non-metallo-beta-lactamase-producing highly meropenem resistant Pseudomonas aeruginosa in a region with bla(vim)-endemicity

Maniati, M.; Pournaras, S.; Tassios, P. T.; Tsakris, A.; Legakis, N. J.; Maniatis, A. N. (2004)

Evaluation of Boronic Acid Disk Tests for Differentiating KPC-Possessing Klebsiella pneumoniae Isolates in the Clinical Laboratory

Tsakris, A.; Kristo, I.; Poulou, A.; Themeli-Digalaki, K.; Ikonomidis, A.; Petropoulou, D.; Pournaras, S.; Sofianou, D. (2009)

The worldwide increase in the occurrence and dissemination of KPC beta-lactamases among gram-negative pathogens makes critical the early detection of these enzymes. Boronic acid disk tests using different antibiotic ...

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