Parcourir par auteur "Koukoulis, G. K."
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Anaplastic lymphoma kinase-positive diffuse large B cell lymphoma: Immunohistochemical and FISH analysis of a rare tumor with unusual clinical presentation
Ioannou, M. G.; Kouvaras, E.; Panagiotidis, P.; Papamichali, R.; Papacharalambous, C.; Koukoulis, G. K.; Androulaki, A. (2013)Anaplastic lymphoma kinase-positive diffuse large B cell lymphoma represents a distinct subtype of diffuse large B cell lymphoma with a characteristic morphology, a distinct immunophenotypic profile, and recurrent ... -
Antimitochondrial antibodies of immunoglobulin G3 subclass are associated with a more severe disease course in primary biliary cirrhosis
Rigopoulou, E. I.; Davies, E. T.; Bogdanos, D. P.; Liaskos, C.; Mytilinaiou, M.; Koukoulis, G. K.; Dalekos, G. N.; Vergani, D. (2007)Background/Aims: Primary biliary cirrhosis (PBC) is characterised by the presence of immunoglobulin (Ig) G antimitochondrial antibodies (AMA), which are routinely detected by indirect immunofluorescence (IFL) using composite ... -
Aurora B kinase in Hodgkin lymphoma: immunohistochemical pattern of expression in neoplastic Hodgkin and Reed-Sternberg cells
Ioannou, M.; Kouvaras, E.; Stathakis, E.; Samara, M.; Koukoulis, G. K. (2014)Aurora B is a member of the chromosomal passenger complex, which is essential for proper completion of mitosis and cell division (cytokinesis). Inappropriate chromosomal segregation and cytokinesis due to deregulated ... -
Autoimmune hepatitis in patients with chronic HBV and HCV infections: Patterns of clinical characteristics, disease progression and outcome
Rigopoulou, E. I.; Zachou, K.; Gatselis, N.; Koukoulis, G. K.; Dalekos, G. N. (2014)We retrospectively investigated the characteristics, patterns of disease progression, outcome and difficulties in the management in 11 patients with concurrent autoimmune hepatitis (AIH) and HBV or HCV infections (5 HCV ... -
Autoimmune hepatitis natural history: a single Greek center experience focused on long-term effect of mycophenolate mofetil as first line treatment
Zachou, K.; Gatselis, N.; Gabeta, S.; Saitis, A. I.; Papadamou, G.; Rigopoulou, E. I.; Koukoulis, G. K.; Dalekos, G. N. (2013) -
Autoimmune hepatitis, one disease with many faces: Etiopathogenetic, clinico-laboratory and histological characteristics
Gatselis, N. K.; Zachou, K.; Koukoulis, G. K.; Dalekos, G. N. (2015)Autoimmune hepatitis (AIH) is an unresolving progressive liver disease of unknown etiology characterized by hypergammaglobulinemia, autoantibodies detection and interface hepatitis. Due to the absence of specific diagnostic ... -
Bortezomib Downregulates MGMT Expression in T98G Glioblastoma Cells
Vlachostergios, P. J.; Hatzidaki, E.; Stathakis, N. E.; Koukoulis, G. K.; Papandreou, C. N. (2013)The efficacy of treatment for glioblastoma multiforme is currently limited by the development of resistance, particularly, but not exclusively, due to the expression of the DNA repair enzyme O6-methylguanine methyltransferase ... -
Cartilage oligomeric matrix protein (COMP) serum levels: a new non-invasive biomarker of liver fibrosis in patients with chronic viral hepatitis
Gabeta, S.; Zachou, K.; Shums, Z.; Gatselis, N.; Koukoulis, G. K.; Norman, G. L.; Dalekos, G. N. (2014) -
Cartilage oligomeric matrix protein (COMP): A novel non-invasive marker for assessing liver cirrhosis and risk of progression to hepatocellular carcinoma
Norman, G. L.; Gatselis, N.; Shums, Z.; Liaskos, C.; Bogdanos, D. P.; Koukoulis, G. K.; Dalekos, G. N. (2014) -
Cartilage oligomeric matrix protein: A novel non-invasive marker for assessing cirrhosis and risk of hepatocellular carcinoma
Norman, G. L.; Gatselis, N. K.; Shums, Z.; Liaskos, C.; Bogdanos, D. P.; Koukoulis, G. K.; Dalekos, G. N. (2015)AIM: To assess serum cartilage oligomeric matrix protein (COMP) as a marker of cirrhosis and risk of progression to hepatocellular carcinoma (HCC). METHODS: A COMP enzyme-linked immunosorbent assay was used to test 187 ... -
A case of membranous nephropathy associated with Sjogren syndrome, polymyositis and autoimmune hepatitis
Stefanidis, I.; Giannopoulou, M.; Liakopoulos, V.; Dovas, S.; Karasavvidou, F.; Zachou, K.; Koukoulis, G. K.; Dalekos, G. N. (2008)Sjogren syndrome (SS) is a chronic systemic autoimmune disease characterized by lymphocylic infiltration of exocrine glands, especially lacrimal and salivary. The immunologic process which occurs in this syndrome is B cell ... -
A case of membranous nephropathy associated with Sjögren syndrome, polymyositis and autoimmune hepatitis
Stefanidis, I.; Giannopoulou, M.; Liakopoulos, V.; Dovas, S.; Karasavvidou, F.; Zachou, K.; Koukoulis, G. K.; Dalekos, G. N. (2008)Sjögren syndrome (SS) is a chronic systemic autoimmune disease characterized by lymphocytic infiltration of exocrine glands, especially lacrimal and salivary. The immunologic process which occurs in this syndrome is B cell ... -
Chronic hepatitis C: Grading, staging, and searching for reliable predictors of outcome
Koukoulis, G. K. (2001) -
Clinical significance of organ- and non-organ-specific autoantibodies on the response to anti-viral treatment of patients with chronic hepatitis C
Gatselis, N. K.; Georgiadou, S. P.; Koukoulis, G. K.; Tassopoulos, N.; Zachou, K.; Liaskos, C.; Hatzakis, A.; Dalekos, G. N. (2006)Background: Development of organ- and non-organ-specific autoantibodies has been reported in hepatitis C virus patients treated with interferon-α plus/minus ribavirin. Aims: To address whether prevalence and the titre of ... -
CLINICAL SIGNIFICANCE OF THE FLUCTUATION OF PRIMARY BILIARY CIRRHOSIS-RELATED AUTOANTIBODIES DURING THE COURSE OF THE DISEASE
Gatselis, N. K.; Zachou, K.; Norman, G. L.; Gabeta, S.; Koukoulis, G. K.; Dalekos, G. N. (2012) -
Clinical significance of the fluctuation of primary biliary cirrhosis-related autoantibodies during the course of the disease
Gatselis, N. K.; Zachou, K.; Norman, G. L.; Gabeta, S.; Papamichalis, P.; Koukoulis, G. K.; Dalekos, G. N. (2013)Primary biliary cirrhosis (PBC) is a chronic cholestatic disease characterized by the presence of antimitochondrial antibodies (AMA). PBC-specific antinuclear antibodies (ANA) have been characterized and associated with ... -
Comparative study of spatial localization of HER-2 and CEP17 signals and of HER-2/CEP17 ratios, in "thin" and "thick" tissue sections
Kouvaras, E.; Papandreou, C. N.; Daliani, D. D.; Athanasiadis, A.; Koukoulis, G. K. (2012)One presumed drawback of performing fluorescence in situ hybridization on routine tissue sections for HER-2 status evaluation in breast carcinomas is nuclear truncation. Therefore, HER-2/CEP 17 ratios were compared in ... -
Comparison of Different Methods for Detecting K-ras Mutations in Colorectal Carcinomas
Samara, M.; Kapatou, K.; Athanassiadis, A.; Koukoulis, G. K. (2009) -
Comparison of simplified score with the revised original score for the diagnosis of autoimmune hepatitis: A new or a complementary diagnostic score?
Gatselis, N. K.; Zachou, K.; Papamichalis, P.; Koukoulis, G. K.; Gabeta, S.; Dalekos, G. N.; Rigopoulou, E. I. (2010)Background and aims: The International Autoimmune Hepatitis Group developed a simplified score for autoimmune hepatitis. We assessed this "new scoring system" and compared it with the International Autoimmune Hepatitis ... -
Correlation of miR-422a, miR-21 and miR-155 analysis with hMSH2 and hMLH1 mRNA expression profiles in non-small cell lung carcinomas and their adjacent normal tissues
Vageli, D.; Doukas, S. G.; Kerenidi, T.; Koukoulis, G. K.; Gourgoulianis, K. I.; Daniil, Z. (2013)