Browsing by Author "Kostikas, K."
Now showing items 1-20 of 68
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The acute effect of smoking in healthy and asthmatic smokers
Papaioannou, A. I.; Koutsokera, A.; Tanou, K.; Kiropoulos, T. S.; Tsilioni, I.; Oikonomidi, S.; Liadaki, K.; Pournaras, S.; Gourgoulianis, K. I.; Kostikas, K. (2010)Background Acute exposure to cigarette smoke is related to airway and systemic inflammation and oxidative stress. Little is known about the acute effect of cigarette smoking in smoking asthmatics. The aim of this study was ... -
Acute exposure to secondhand smoke is associated with endogenous lung acidosis and obstructive pulmonary disorder
Dinas, P.; Flouris, A.; Minas, M.; Kostikas, K.; Mavromanolaki, I.; Terzi, I.; Kavvalakis, M.; Tzatzarakis, M.; Tsatsakis, A. (2010) -
Acute impact of active and passive electronic cigarette smoking on serum cotinine and lung function
Flouris, A. D.; Chorti, M. S.; Poulianiti, K. P.; Jamurtas, A. Z.; Kostikas, K.; Tzatzarakis, M. N.; Hayes, A. W.; Tsatsakis, A. M.; Koutedakis, Y. (2013)Context: Electronic cigarettes (e-cigarettes) are becoming increasingly popular yet their effects on health remain unknown. Objective: To conduct the first comprehensive and standardized assessment of the acute impact of ... -
Acute phase markers for the differentiation of infectious and malignant pleural effusions
Kiropoulos, T. S.; Kostikas, K.; Oikonomidi, S.; Tsilioni, I.; Nikoulis, D.; Germenis, A.; Gourgoulianis, K. I. (2007)Acute-phase markers, such as C-reactive protein (CRP), interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α), have been studied in inflammatory and malignant disorders. We examined the diagnostic value of these ... -
Adrenomedullin optimises mortality prediction in COPD patients
Brusse-Keizer, M.; Zuur-Telgen, M.; van der Palen, J.; VanderValk, P.; Kerstjens, H.; Boersma, W.; Blasi, F.; Kostikas, K.; Milenkovic, B.; Tamm, M.; Stolz, D. (2015)Background: Current multicomponent scores that predict mortality in COPD patients might underestimate the systemic component of COPD. Therefore, we evaluated the accuracy of circulating levels of proadrenomedullin (MR-proADM) ... -
Adrenomedullin refines mortality prediction by the BODE index in COPD: the "BODE-A" index
Stolz, D.; Kostikas, K.; Blasi, F.; Boersma, W.; Milenkovic, B.; Lacoma, A.; Louis, R.; Aerts, J. G.; Welte, T.; Torres, A.; Rohde, G. G. U.; Boeck, L.; Rakic, J.; Scherr, A.; Hertel, S.; Giersdorf, S.; Tamm, M. (2014)The BODE (body mass index, airflow obstruction, dyspnoea, exercise capacity) index is well-validated for mortality prediction in chronic obstructive pulmonary disease (COPD). Concentrations of plasma pro-adrenomedullin, a ... -
Amyloid cardiomyopathy presenting as persistent symptomatic pleural effusions
Daniil, Z.; Zakynthinos, E.; Papageorgiou, E.; Loannou, M.; Kostikas, K.; Gourgoulianis, K. (2005)A 73-year-old male presented with dyspnea and bilateral transudative pleural effusions that persisted despite aggressive diuresis. No etiology had been established despite an extensive workout. The only abnormal finding ... -
Anti-Interleukin-5 Therapy and Severe Asthma
Zarogiannis, S.; Gourgoulianis, K. I.; Kostikas, K. (2009) -
Anti-interleukin-5 therapy and severe asthma [1]
Zarogiannis, S.; Gourgoulianis, K. I.; Kostikas, K. (2009) -
The Association of Metabolic Syndrome with Adipose Tissue Hormones and Insulin Resistance in Patients with COPD without Co-morbidities
Minas, M.; Kostikas, K.; Papaioannou, A. I.; Mystridou, P.; Karetsi, E.; Georgoulias, P.; Liakos, N.; Pournaras, S.; Gourgoulianis, K. I. (2011)Chronic obstructive pulmonary disease (COPD) and metabolic syndrome represent common causes of morbidity and mortality in ageing populations. The effect of the co-existence of COPD and metabolic syndrome on adipose tissue ... -
Association of TLR4-T399I Polymorphism with Chronic Obstructive Pulmonary Disease in Smokers
Speletas, M.; Merentiti, V.; Kostikas, K.; Liadaki, K.; Minas, M.; Gourgoulianis, K.; Germenis, A. E. (2009)Tobacco smoking has been considered the most important risk factor for chronic obstructive pulmonary disease (COPD) development. However, not all smokers develop COPD and other environmental and genetic susceptibility ... -
Associations between BODE Index and Systemic Inflammatory Biomarkers in COPD
Gaki, E.; Kontogianni, K.; Papaioannou, A. I.; Bakakos, P.; Gourgoulianis, K. I.; Kostikas, K.; Alchanatis, M.; Papiris, S.; Loukides, S. (2011)Background: COPD is a multicomponent disease and systemic inflammation represents one of the possible mechanisms responsible for its systemic manifestations, including skeletal muscle weakness and cachexia. Fat-free mass ... -
Biomarkers in the exhaled breath condensate of healthy adults: Mapping the path towards reference values
Koutsokera, A.; Loukides, S.; Gourgoulianis, K. I.; Kostikas, K. (2008)The need for non-invasive assessment of airway inflammation is imperative, since inflammatory airway diseases, such as asthma and COPD, are characterized by variation in their clinical presentation throughout their course. ... -
Biomarkers Obtained by Non-Invasive Methods in Patients with COPD: Where do we Stand, what do we Expect?
Hillas, G.; Loukides, S.; Kostikas, K.; Bakakos, P. (2009)Recently, there has been widespread interest in the use of non-invasive methods for the assessment of airway inflammation in a variety of lung diseases including chronic obstructive pulmonary disease ( COPD). Sputum induction ... -
BMI and gastroesophageal reflux in women
Kostikas, K.; Papaioannou, A. I.; Gourgoulianis, K. I. (2006) -
BMI and gastroesophageal reflux in women [7]
Kostikas, K.; Papaioannou, A. I.; Gourgoulianis, K. I. (2006) -
Body Composition in Severe Refractory Asthma: Comparison with COPD Patients and Healthy Smokers
Minas, M.; Papaioannou, A. I.; Tsaroucha, A.; Daniil, Z.; Hatzoglou, C.; Sgantzos, M.; Gourgoulianis, K. I.; Kostikas, K. (2010)Background: Body composition is an important parameter for patients with chronic obstructive pulmonary disease (COPD) whereas the association between asthma and obesity is not fully understood. The impact of severe refractory ... -
Clinical implications for Vascular Endothelial Growth Factor in the lung: friend or foe?
Papaioannou, A. I.; Kostikas, K.; Kollia, P.; Gourgoulianis, K. I. (2006)Vascular endothelial growth factor (VEGF) is a potent mediator of angiogenesis which has multiple effects in lung development and physiology. VEGF is expressed in several parts of the lung and the pleura while it has been ... -
Clinical, functional and biochemical changes during recovery from COPD exacerbations
Koutsokera, A.; Kiropoulos, T. S.; Nikoulis, D. J.; Daniil, Z. D.; Tsolaki, V.; Tanou, K.; Papaioannou, A. I.; Germenis, A.; Gourgoulianis, K. I.; Kostikas, K. (2009)The pathways underlying chronic obstructive pulmonary disease exacerbations (ECOPD) remain unclear. This study describes the clinical., functional and biochemical changes during recovery from ECOPD. Thirty hospitalized ... -
Comparison of a network of primary care physicians and an open spirometry programme for COPD diagnosis
Konstantikaki, V.; Kostikas, K.; Minas, M.; Batavanis, G.; Daniil, Z.; Gourgoulianis, K. I.; Hatzoglou, C. (2011)Background: Early diagnosis of Chronic Obstructive Pulmonary Disease (COPD) remains the cornerstone for effective management. In this study we compared an open spirometry programme and a case-finding programme providing ...