Πλοήγηση ανά Συγγραφέα "Kostikas, K."
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COPD prevalence and the differences between newly and previously diagnosed COPD patients in a spirometry program
Minas, M.; Hatzoglou, C.; Karetsi, E.; Papaioannou, A. I.; Tanou, K.; Tsaroucha, R.; Gogou, E.; Gourgoulianis, K. I.; Kostikas, K. (2010)Aims: To evaluate the prevalence and severity of COPD in a primary care population participating in a spirometry program. Differences between newly and previously diagnosed COPD patients were identified. Methods: A spirometry ... -
Could IFN-γ predict the development of residual pleural thickening in tuberculous pleurisy?
Gerogianni, I.; Papala, M.; Tsopa, P.; Zigoulis, P.; Dimoulis, A.; Kostikas, K.; Kiropoulos, T.; Gourgoulianis, K. I. (2008)Could IFN-γ predict the development of residual pleural thickening tuberculous pleurisy? I. Gerogianni, M. Papala, P. Tsopa, P. Zigoulis, A. Dimoulis, K. Kostikas, T. Kiropoulos, KI Gourgoulianis. Background. The aim of ... -
d-ROMs test detects ceruloplasmin, not oxidative stress
Kostikas, K.; Papageorgiou, E.; Kiropoulos, T. S.; Gourgoulianis, K. I. (2006) -
Diagnostic accuracy of biomarkers of oxidative stress in parapneumonic pleural effusions
Tsilioni, I.; Kostikas, K.; Kalomenidis, I.; Oikonomidi, S.; Tsolaki, V.; Minas, M.; Gourgoulianis, K. I.; Kiropoulos, T. S. (2011)P>Background The imbalance between oxidants and antioxidants is referred to as oxidative stress and has been associated with various respiratory disorders. The aim of this study was the assessment of 8-isoprostane (8-iso-PGF(2 ... -
Do we overtreat mild persistent asthma?
Loukides, S.; Kostikas, K.; Bakakos, P. (2009) -
Effects of electronic cigarette and tobacco cigarette smoking on complete blood count
Kouretas, D.; Poulianiti, K.; Chorti, M.; Jamurtas, A.; Kostikas, K.; Tzatzarakis, M.; Koutedakis, Y.; Flouris, A.; Tsatsakis, A. (2012) -
Epidemiology and clinical significance of mycobacterial respiratory infections in Central Greece
Gerogianni, I.; Papala, M.; Kostikas, K.; Petinaki, E.; Gourgoulianis, K. I. (2008)SETTING: A 750-bed tertiary referral hospital in Central Greece. OBJECTIVE: To determine the incidence of non-tuberculous mycobacteria (NTM) respiratory infection based on the isolation of NTM in respiratory specimens, to ... -
Exertional Hypoxemia in Stable COPD Is Common and Predicted by Circulating Proadrenomedullin
Stolz, D.; Boersma, W.; Blasi, F.; Louis, R.; Milenkovic, B.; Kostikas, K.; Aerts, J. G.; Rohde, G.; Lacoma, A.; Rakic, J.; Boeck, L.; Castellotti, P.; Scherr, A.; Marin, A.; Hertel, S.; Giersdorf, S.; Torres, A.; Welte, T.; Tamm, M. (2014)BACKGROUND: The prevalence of exertional hypoxemia in unselected patients with COPD is unknown. Intermittent hypoxia leads to adrenomedullin (ADM) upregulation through the hypoxia-inducible factor-1 pathway. We aimed to ... -
Exhaled breath condensate in patients with asthma: implications for application in clinical practice
Kostikas, K.; Koutsokera, A.; Papiris, S.; Gourgoulianis, K. I.; Loukides, S. (2008)Exhaled breath condensate (EBC) analysis, a rather appealing and promising method, can be used to evaluate conveniently and non-invasively a wide range of molecules from the respiratory tract, and to understand better the ... -
Exhaled breath condensate pH as a biomarker of COPD severity in ex-smokers
Papaioannou, A. I.; Loukides, S.; Minas, M.; Kontogianni, K.; Bakakos, P.; Gourgoulianis, K. I.; Alchanatis, M.; Papiris, S.; Kostikas, K. (2011)Endogenous airway acidification, as assessed by exhaled breath condensate (EBC) pH, is present in patients with stable COPD. The aim of this study was to measure EBC pH levels in a large cohort of COPD patients and to ... -
Exhaled Nitric Oxide in Asthma in Adults: The End is the Beginning?
Kostikas, K.; Minas, M.; Papaioannou, A. I.; Papiris, S.; Dweik, R. A. (2011)Approximately 20 years after the initial report of the measurement of exhaled nitric oxide (NO) in the exhaled air of humans, numerous publications have evaluated the possible applications of the fraction of exhaled NO ... -
Exhaled NO and exhaled breath condensate pH in the evaluation of asthma control
Kostikas, K.; Papaioannou, A. I.; Tanou, K.; Giouleka, P.; Koutsokera, A.; Minas, M.; Papiris, S.; Gourgoulianis, K. I.; Taylor, D. R.; Loukides, S. (2011)Background: Asthma is a chronic inflammatory airways disorder. However, no biomarker of airways inflammation has been included in the assessment of asthma control. Objective: To evaluate exhaled NO (FeNO) and exhaled breath ... -
Exhaled NO may predict loss of asthma control: the effect of concomitant allergic rhinitis
Papaioannou, A. I.; Minas, M.; Tanou, K.; Gourgoulianis, K. I.; Kostikas, K. (2009) -
Exposure to secondhand smoke promotes sympathetic activity and cardiac muscle cachexia
Flouris, A. D.; Dinas, P. C.; Tzatzarakis, M. N.; Metsios, G. S.; Kostikas, K.; Jamurtas, A. Z.; Tsatsakis, A. M.; Koutedakis, Y. (2014)Recent trials demonstrated that a single brief exposure to secondhand smoke (SHS) generates acute adverse health effects. We evaluated the acute (immediately after exposure) and short-term (0.5, 1, 2, 3 and 4 h after ... -
Fetuin-A is Associated with Disease Severity and Exacerbation Frequency in Patients with COPD
Minas, M.; Mystridou, P.; Georgoulias, P.; Pournaras, S.; Kostikas, K.; Gourgoulianis, K. I. (2013)Fetuin-A is a liver protein that may serve as an inhibitor of systemic inflammation in humans. In the present study we assessed the levels of fetuin-A in COPD patients in stable condition and on exacerbation in an attempt ... -
Global assessment of the COPD patient: Time to look beyond FEV1?
Papaioannou, A. I.; Loukides, S.; Gourgoulianis, K. I.; Kostikas, K. (2009)COPD is a diverse disease entity with multiple dimensions that uniquely define the patient's performance, morbidity and mortality. FEV1 is both the traditional metric used to define the progression of COPD as well as the ... -
Hemoglobin, erythropoietin and systemic inflammation in exacerbations of chronic obstructive pulmonary disease
Markoulaki, D.; Kostikas, K.; Papatheodorou, G.; Koutsokera, A.; Alchanatis, M.; Bakakos, P.; Gourgoulianis, K. I.; Roussos, C.; Koulouris, N. G.; Loukides, S. (2011)Background: Systemic inflammation may represent a possible cause of anemia. Previous data support that anemic patients with COPD present high erythropoietin (EPO) levels, suggestive of EPO resistance, possibly mediated ... -
Increased oxidative stress in exudative pleural effusions - A new marker for the differentiation between exudates and transudates?
Papageorgiou, E.; Kostikas, K.; Kiropoulos, T.; Karetsi, E.; Mpatavanis, G.; Gourgoulianis, K. I. (2005)Study objectives: Oxidative stress has been associated with various respiratory disorders. We tested the hypothesis that exudates would present higher levels of oxidative stress compared to transudates, expressing the ... -
Inflammatory and oxidative stress biomarkers in allergic rhinitis: the effect of smoking
Tanou, K.; Koutsokera, A.; Kiropoulos, T. S.; Maniati, M.; Papaioannou, A. I.; Georga, K.; Zarogiannis, S.; Gourgoulianis, K. I.; Kostikas, K. (2009)Accumulating evidence confirms the presence of pan-airway inflammation in allergic rhinitis patients. Smoking is known to affect the asthmatic airway inflammation. However, no study has evaluated the impact of smoking on ... -
Isocapnic Cold Air Challenge in Patients with COPD: Are There any Predisposing Factors?
Kostikas, K.; Koutsoumbou, S.; Karamanis, T.; Papatheodorou, G.; Loukides, S. (2008)Cold air hyperventilation is an indirect challenge (cold air challenge, CACh) with high specificity and low sensitivity in defining asthmatic subjects. A small proportion of chronic obstructive pulmonary disease (COPD) ...