Parcourir par auteur "Giannouli, S."
Voici les éléments 1-17 de 17
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Autoimmune phenomena in myelodysplastic syndromes: a 4-yr prospective study
Giannouli, S.; Voulgarelis, M.; Zintzaras, E.; Tzioufas, A. G.; Moutsopoulos, H. M. (2004)Objective. To determine the clinical aspects and evolution of autoimmune inflammatory manifestations (AIMs) in patients with myelodysplastic syndrome (MDS) and ascertain the prognostic implications of these manifestations ... -
Autoimmune phenomena in myelodysplastic syndromes: A four year prospective study
Giannouli, S.; Voulgarelis, M.; Zintzaras, E.; Tzioufas, A. G.; Moutsopoulos, H. M. (2004) -
Detection of mutations in the FemXAB protein family in oxacillin-susceptible mecA-positive Staphylococcus aureus clinical isolates
Giannouli, S.; Labrou, M.; Kyritsis, A.; Ikonomidis, A.; Pournaras, S.; Stathopoulos, C.; Tsakris, A. (2010)Methicillin-resistant Staphylococcus aureus (MRSA) strains that express the mecA gene but are oxacillin susceptible (OS-MRSA; oxacillin MIC < 2 mg/L) are increasingly reported. To gain molecular and functional insights on ... -
EFFECT OF TRANSOSSEOUS APPLICATION OF LOW-INTENSITY ULTRASOUND AT THE TENDON GRAFT-BONE INTERFACE HEALING: GENE EXPRESSION AND HISTOLOGICAL ANALYSIS IN RABBITS
Papatheodorou, L. K.; Malizos, K. N.; Poultsides, L. A.; Hantes, M. E.; Grafanaki, K.; Giannouli, S.; Ioannou, M. G.; Koukoulis, G. K.; Protopappas, V. C.; Fotiadis, D. I.; Stathopoulos, C. (2009)The present study investigates the effect of transosseous low-intensity pulsed ultrasound (LiUS) on the healing at tendon graft-bone interface, in molecular and histological level. The anterior cruciate ligament (ACL) in ... -
Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis: A Systematic Review and Meta-Analysis of Dosage Regimens
Zintzaras, E.; Dahabreh, I. J.; Giannouli, S.; Voulgarelis, M.; Moutsopoulos, H. M. (2008)Background: Because of its long-term effectiveness in clinical practice, methotrexate (MTX) is currently the preferred disease-modifying antirheumatic drug (DMARD) for patients with active rheumatoid arthritis (RA). However, ... -
JAK2 V617F-POSITIVE CHRONIC EOSINOPHILIC LEUKEMIA: CLINICAL, LABORATORY AND MOLECULAR DEFINITION OF A DISTINCT DISEASE SUBTYPE
Zoi, K.; Dahabreh, I. J.; Zoi, C.; Helbig, G.; Krzemien, S.; Gota, V.; Speletas, M.; Giannouli, S.; Palliou, A.; Stefanoudaki, K.; Harhalakis, N.; Vassilopoulos, G.; Kotsopoulou, M.; Tsirigotis, P.; Moutsopoulos, H. M.; Loukopoulos, D.; Voulgarelis, M. (2009) -
Lupus thrombocytopenia: clinical implications and prognostic significance
Ziakas, P. D.; Giannouli, S.; Zintzaras, E.; Tzioufas, A. G.; Voulgarelis, M. (2005)Objectives: To clarify clinical manifestations, association with disease activity, and prognostic impact of thrombocytopenia using simple and reliable indices. Methods: 632 patients were reviewed retrospectively. Fifty ... -
A meta-analysis of genotypes and haplotypes of methylenetetrahydrofolate reductase gene polymorphisms in acute lymphoblastic leukemia
Zintzaras, E.; Koufakis, T.; Ziakas, P. D.; Rodopoulou, P.; Giannouli, S.; Voulgarelis, M. (2006)A meta-analysis of case-control studies that investigated the association between the C677T and/or A1298C polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and acute lymphoblastic leukemia (ALL) was ... -
Mitochondrial tRNA mutations - Clinical and functional perturbations
Zifa, E.; Giannouli, S.; Theotokis, P.; Stamatis, O.; Mamuris, Z.; Stathopoulos, C. (2007)During the last decade, there has been a progressive accumulation of reports that connect the identification of specific mitochondrial tRNA gene mutations to severe disorders in human. As a result, mitochondrial tRNA genes ... -
Mitochondrial tRNA mutations: Clinical and functional perturbations
Zifa, E.; Giannouli, S.; Theotokis, P.; Stamatis, C.; Mamuris, Z.; Stathopoulos, C. (2007)During the last decade, there has been a progressive accumulation of reports that connect the identification of specific mitochondrial tRNA gene mutations to severe disorders in human. As a result, mitochondrial tRNA genes ... -
On the role of an unusual tRNA(Gly) isoacceptor in Staphylococcus aureus
Giannouli, S.; Kyritsis, A.; Malissovas, N.; Becker, H. D.; Stathopoulos, C. (2009)In the available Staphylococcus aureus genomes, four different genes have been annotated to encode tRNA(Gly) isoacceptors. Besides their prominent role in protein synthesis, some of them also participate in the formation ... -
Recruitment of mitochondrial tRNA genes as auxiliary variability markers for both intra- and inter-species analysis: The paradigm of brown hare (Lepus europaeus)
Stamatis, C.; Giannouli, S.; Suchentrunk, F.; Sert, H.; Stathopoulos, C.; Mamuris, Z. (2008)We sequenced and analyzed the mitochondrial tRNA(Thr) and tRNA(Pro) genes from brown hare (Lepus europaeus) individuals of different geographic distribution and we investigated the role of various nucleotide substitutions ... -
RNA-Mediated therapeutics: From gene inactivation to clinical application
Kalavrizioti, D.; Vourekas, A.; Stamatopoulou, V.; Toumpeki, C.; Giannouli, S.; Stathopoulos, C.; Drainas, D. (2006)The specific targeting and inactivation of gene expression represents nowdays the goal of the mainstream basic and applied biomedical research. Both researchers and pharmaceutical companies, taking advantage of the vast ... -
The role of MTHFR gene in multiple myeloma
Zintzaras, E.; Giannouli, S.; Rodopoulou, P.; Voulgarelis, M. (2008)Case-control studies investigating associations between multiple myeloma (MM) and the C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) have provided controversial results. In an attempt to ... -
A single tRNA base pair mediates bacterial tRNA-dependent biosynthesis of asparagine
Bailly, M.; Giannouli, S.; Blaise, M.; Stathopoulos, C.; Kern, D.; Becker, H. D. (2006)In many prokaryotes and in organelles asparagine and glutamine are formed by a tRNA-dependent amidotransferase (AdT) that catalyzes amidation of aspartate and glutamate, respectively, mischarged on tRNA(Asn) and tRNA(Gln). ... -
Studies on the role of a pseudogene encoding an atypical tRNA(Gly) in Staphylococcus aureus
Giannouli, S.; Kyritsis, A.; Stathopoulos, C. (2008) -
Transosseous application of low-intensity ultrasound at the tendon-bone interface affects the healing rate and up-regulates simultaneously the expression of collagen type i and tRNAGly
Papatheodorou, L. K.; Grafanaki, K.; Giannouli, S.; Fotiadis, D. I.; Stathopoulos, C.; Malizos, K. N. (2008)The present study investigates the effect of transosseous low-intensity pulsed ultrasound (LiUS) during lingamentization process on the healing at tendon graft-bone interface in rabbits. Analysis of the RT-PCR products ...