Πλοήγηση ανά Θέμα "CANCER"
Αποτελέσματα 1-20 από 69
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Activation of mTOR signaling in medullary and aggressive papillary thyroid carcinomas
(2011)Background. Because mammalian target of rapamycin (mTOR) may be involved in thyroid carcinogenesis, we investigated the expression and activation patterns of mTOR signaling proteins in thyroid carcinoma cells and tumors ... -
Advanced intrahepatic cholangiocarcinoma in hepatitis C virus-related decompensated cirrhosis: case report and review of the literature
(2003)A 75-year-old man with no known previous liver disease was admitted to our institution because of right pleural effusion, backache, and pain in the upper right quadrant. Physical and laboratory work-up revealed decompensated ... -
Albumin possesses intrinsic enolase activity towards dihydrotestosterone which can differentiate benign from malignant breast tumors
(1999)Serum albumin was found to possess enolase activity towards the dihydrotestesterone (DHT) molecule, converting it from its 3-keto to 3-enol form. This activity was accompanied by albumin during all stages of purification, ... -
Allergy-associated symptoms in relation to childhood non-Hodgkin's as contrasted to Hodgkin's lymphomas: A case-control study in Greece and meta-analysis
(2012)An increase of the prevalence of childhood allergic diseases and the incidence of childhood Hodgkin's (HL) and non-Hodgkin's lymphoma (NHL) were reported in the late 20th century. Among adults, several studies point to an ... -
Alterations of Deadenylase Expression in Acute Leukemias: Evidence for Poly(A)-Specific Ribonuclease as a Potential Biomarker
(2012)Background/Aims: The degradation of mRNA is a key process in the control of gene expression correlated to anomalous cell proliferation. The rate-limiting step of mRNA degradation is the removal of the poly(A) tail by ... -
Antioxidant and chemopreventive properties of polyphenolic compounds derived from Greek legume plant extracts
(2008)Recently, phytochemical compounds present in legumes have gained a lot of interest because they are considered to be possible chemopreventive agents. In the present study, 14 polyphenolic compounds were extracted and ... -
Application value of 3T H-1-magnetic resonance spectroscopy in diagnosing breast tumors
(2013)Background: Assessment of breast lesions with magnetic resonance imaging (MRI) provides a means for lesion detection and diagnosis. Proton (hydrogen-1) magnetic resonance spectroscopy (H-1-MRS) has been proposed as a useful ... -
Assessment of polyphenolic content, antioxidant activity, protection against ROS-induced DNA damage and anticancer activity of Vitis vinifera stem extracts
(2013)Grape extracts and wine have been studied widely due to their beneficial effects on human health. However, there are only few studies from grape stems extracts. Therefore, the main objective of the present study was the ... -
Association between periodontal disease and stroke
(2012)Objective: Periodontitis is a very common human infection. There is evidence that periodontitis is associated with cerebrovascular disease (CVD) and stroke. The aim of this study is to examine the relationship between ... -
Association of allelic loss at the FHIT locus and p53 alterations with tumour kinetics and chromosomal instability in non-small cell lung carcinomas (NSCLCs)
(2001)The FHIT gene, located at the FRA3B fragile site of chromosome 3p14.2, encodes a 16.8 kD homologue of the yeast enzyme diadenosine tetraphosphate (Ap(4)A) hydrolase, Frequent allelic losses at this region in various ... -
Association of interleukin-1A, interleukin-1B and interleukin-1 receptor antagonist gene polymorphisms with multiple myeloma
(2007)Interleukin-1 (IL-1) is a cytokine involved in the maturation and proliferation of B cells and plays a significant role in the development of lytic bone lesions, a major clinical feature of multiple myeloma (MM) patients. ... -
An Association Study between Hypoxia Inducible Factor-1alpha (HIF-1 alpha) Polymorphisms and Osteonecrosis
(2013)Bone hypoxia resulting from impaired blood flow is the final pathway for the development of osteonecrosis (ON). The aim of this study was to evaluate if HIF-1 alpha, the major transcription factor triggered by hypoxia, is ... -
Aurora B kinase in Hodgkin lymphoma: immunohistochemical pattern of expression in neoplastic Hodgkin and Reed-Sternberg cells
(2014)Aurora B is a member of the chromosomal passenger complex, which is essential for proper completion of mitosis and cell division (cytokinesis). Inappropriate chromosomal segregation and cytokinesis due to deregulated ... -
Breeding Objectives and Selection Criteria for Milk Thistle Silybum marianum (L.) Gaertn. Improvement
(2013)Milk thistle [Silybum marianum (L.) Gaertn.] is an important medicinal-industrial plant. The medicinal compounds of milk thistle are derived from its seeds. The plant is commercially cultivated for the production of ... -
CD10 Is Inversely Associated with Nuclear Factor-Kappa B and Predicts Biochemical Recurrence after Radical Prostatectomy
(2012)Introduction: The cell surface endopeptidase CD10 (neutral endopeptidase) and nuclear factor-kappa B (NF-kappa B) have been independently associated with prostate cancer (PC) progression. We investigated the correlations ... -
Characterization of breast lesions with CE-MR multimodal morphological and kinetic analysis: Comparison with conventional mammography and high-resolution ultrasound
(2009)Objective: Evaluation of the diagnostic value of magnetic resonance mammography and comparison with conventional mammography and ultrasonography in cases of women with suspicious breast lesions. Subjects and methods: ... -
Clinical and experimental evidence of bcl-2 involvement in the response to photodynamic therapy
(2001)Purpose: The role of apoptosis related proteins in the response of human malignancies to photodynamic therapy (PDT) is under investigation. The aim of the study was to examine the role of p53 and of bcl-2 protein expression ... -
The contribution of diffusion tensor imaging and magnetic resonance spectroscopy for the differentiation of breast lesions at 3T
(2014)Background: Conventional breast magnetic resonance imaging (MRI), including dynamic contrast-enhanced MR mammography (DCE-MRM), may lead to ambiguous diagnosis and unnecessary biopsies. Purpose: To investigate the contribution ... -
Correlation between radiation-induced telomerase activity and human telomerase reverse transcriptase mRNA expression in HeLa cells
(2006)Purpose: To quantify and correlate human telomerase reverse transcriptase (hTERT) mRNA expression with telomerase activity (TA) after ionizing irradiation of HeLa cells. Materials and methods: TA and hTERT mRNA expression ... -
Dietary administration of tannic acid lowers plasminogen activator activity in the liver of C3H hepatoma bearing male mice
(2000)Background: This study was undertaken to investigate if low-dose dietary administration of tannic acid exerts its chemopreventative activity on hepatocarcinogenesis in male C3H mice through changes of plasminogen activator ...