Browsing by Subject "Alzheimer's disease"
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Alzheimer's disease treated patients showed different patterns for oxidative stress and inflammation markers
(2013)Alzheimer's disease (AD) is the most common type of dementia accounting for 60-80% of the reported cases. The aim of this study was to evaluate levels of certain parameters of oxidative stress and markers of endothelial ... -
Can a Virtual Reality Cognitive Training Application Fulfill a Dual Role? Using the Virtual Supermarket Cognitive Training Application as a Screening Tool for Mild Cognitive Impairment
(2015)Background: Recent research advocates the potential of virtual reality (VR) applications in assessing cognitive functions highlighting the possibility of using a VR application for mild cognitive impairment (MCI) screening. ... -
Depressive symptoms in Alzheimer's disease: Natural course and temporal relation to function and cognitive status
(2005)OBJECTIVES: To examine the natural course of depressive symptoms in patients with probable Alzheimer's disease (AD), specifically, the temporal relationship between depressive symptoms, function, and cognitive status. ... -
Do Patients with Alzheimer's Disease Draw like Young Children? An Exploratory Study
(2015)Background: Previous studies have shown that AD patients present a stepwise regression to their cognitive functioning from a mature adult to that of an infant. Objectives: The present study aimed to compare Alzheimer's ... -
Evaluation of the cholinergic hypothesis in Alzheimer's disease with neuropsychological methods
(2015)This study aimed at evaluating the cholinergic hypothesis in Alzheimer's disease (AD) patients utilizing the pupillometry method, cognitive tests and Hamilton Depression Rating Scale (HAM-D), as well as to examine whether ... -
The Hellenic Longitudinal Investigation of Aging and Diet (HELIAD): Rationale, Study Design, and Cohort Description
(2014)Background: Accumulating epidemiological evidence from several populations supports the important role of the Mediterranean-type diet (MeDi) in reducing the risk for age-related diseases such as Alzheimer's disease (AD). ... -
Perfusion SPECT studies with mapping of Brodmann areas in differentiating Alzheimer's disease from frontotemporal degeneration syndromes
(2012)Objectives The aim of this study was to evaluate the contribution of brain perfusion single-photon emission computed tomography (SPEC) studies with mapping of Brodmann areas (BAs) in the differential diagnosis between ... -
Protein misfolding in neurodegenerative diseases
(2004)A common pathogenic mechanism shared by diverse neurodegenerative disorders, like Alzheimer's disease, Parkinson's disease, Huntington's disease and transmissible spongiform encephalopathies, may be altered protein homeostasis ... -
Synucleins: New prospects in the diseases of the nervous system
(2003)Research in the molecular neuroscience field in the last years has revealed a family of proteins called synucleins, present in abundance in the nervous system. Synucleins are small, heat-stable and soluble proteins with a ... -
A tool to monitor and support physical exercise interventions for MCI and AD patients
(2014)This paper presents a tool to monitor and support the execution of common physical exercise interventions targeting people with Mild Cognitive Impairment (MCI), Alzheimer's Disease (AD) and elderly in general. Our tool ...