Πλοήγηση ανά Θέμα "particle size"
Αποτελέσματα 1-18 από 18
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Application of a One-Dimensional Computational Model for the Prediction of Deposition from a Dry Powder Inhaler
(2017)Background: Accurate prediction of the regional deposition of inhaled dry powders as a function of powder properties and breathing pattern is a long-term research goal for pulmonary drug delivery. In the present work, ... -
Application of efficient nanoparticles for early diagnosis and treatment of cancer
(2015)Cancer is considered as a prevalent cause of human deaths and undoubtedly, is the most complex disease with multiple cellular physiological systems involved. During the last decade, the application of nanotechnological ... -
Carbon nanotubes and other engineered nanoparticles induced pathophysiology on mesothelial cells and mesothelial membranes
(2018)Nanoparticles have great potential for numerous applications due to their unique physicochemical properties. However, concerns have been raised that they may induce deleterious effects on biological systems. There is ... -
Development and evaluation of liposomal nanoparticles incorporating dimethoxycurcumin. In vitro toxicity and permeability studies
(2022)Liposomes belong to the class of drug delivery nanosystems and are widely used for the incorporation and delivery of lipophilic drug molecules. The present work deals with the physicochemical characterization of different ... -
The effect of alveolar mixing on particle retention and deposition investigated by a dynamic single-path model
(2020)A dynamic, single-path model is developed for dry powder transport in the lungs. The model differentiates between particle behavior in the respiratory bronchioles and alveolar ducts on one hand and inside the alveoli on ... -
Enhanced oxygen reduction and methanol oxidation reaction over self-assembled Pt-M (M = Co, Ni) nanoflowers
(2022)Herein, we introduce a facile approach to synthesize a unique class of Pt-M (M = Ni, Co) catalysts with a nanoflower structure for boosting both oxygen reduction reaction (ORR) and methanol oxidation reaction (MOR). By ... -
Factors mediating lipofection potency of a series of cationic phosphonolipids in human cell lines
(2006)A series of cationic liposomes known as cationic phosphonolipids (CPs) were evaluated as vehicles for in vitro gene transfer in K562 erythroleukemia cells and 5637 epithelial carcinoma cells. For each CP and target cell ... -
The health impact of Saharan dust exposure
(2019)Air pollution is a high priority global health concern. The health damaging effects of ambient particulate matter (PM), a component of air pollution, are extensively documented, with 1.4% of deaths worldwide resulting from ... -
Intensity of Humoral Immune Responses, Adverse Reactions, and Post-Vaccination Morbidity after Adenovirus Vector-Based and mRNA Anti-COVID-19 Vaccines
(2022)The aim of the study was to compare mRNA vaccine BNT162b2 with adenovirus vector- based vaccines in terms of presence of adverse reactions, immunogenicity, and protection against COVID-19. A total of 270 individuals were ... -
Nanosystems for the encapsulation of natural products: The case of chitosan biopolymer as a matrix
(2020)Chitosan is a cationic natural polysaccharide, which has emerged as an increasingly interesting biomaterialover the past few years. It constitutes a novel perspective in drug delivery systems and nanocarriers’ formulations ... -
A numerical model for aggregations formation and magnetic driving of spherical particles based on OpenFOAM®
(2017)Background and objective This work presents a numerical model for the formation of particle aggregations under the influence of a permanent constant magnetic field and their driving process under a gradient magnetic field, ... -
On the magnetic aggregation of Fe3O4 nanoparticles
(2021)Background and objective In-vivo MRI-guided drug delivery concept is a personalized technique towards cancer treatment. A major bottleneck of this method, is the weak magnetic response of nanoparticles. A crucial improvement ... -
Prediction of particle deposition in the lungs based on simple modeling of alveolar mixing
(2016)A simplified model of particle deposition in the lungs has been developed and implemented, based on the hypothesis that perfect mixing takes place in the alveolar volume of each airway generation. This key idea is combined ... -
Silver nanoparticles alter cell adhesion and proliferation of sheep primary mesothelial cells
(2018)Background: Human exposure to engineered nanoparticles has been linked to pleural effusion, inflammation and fibrosis. Silver nanoparticles (AgNPs) are widely used in medical and domestic products, increasing the risk of ... -
Simulation of magnetic nanoparticles crossing through a simplified blood-brain barrier model for Glioblastoma multiforme treatment
(2021)Background and Objectives: Glioblastoma multiforme is considered as one of the most aggressive types of cancer, while various treatment techniques have been proposed. Magnetic nanoparticles (MNPs) loaded with drug and ... -
Small extracellular vesicles in pre-therapy plasma predict clinical outcome in non-small-cell lung cancer patients
(2021)The potential use of plasma-derived small extracellular vesicles (sEV) as predictors of response to therapy and clinical outcome in chemotherapy-naïve patients with non-small-cell lung cancer (NSCLC) was explored. sEV were ... -
Source apportionment of PM10 and PM2.5 in major urban Greek agglomerations using a hybrid source-receptor modeling process
(2017)A hybrid source-receptor modeling process was assembled, to apportion and infer source locations of PM10 and PM2.5 in three heavily-impacted urban areas of Greece, during the warm period of 2011, and the cold period of ... -
Transcriptome Analysis Identifies Immune Markers Related to Visceral Leishmaniasis Establishment in the Experimental Model of BALB/c Mice
(2019)Visceral leishmaniasis (VL) caused by Leishmania donovani and L. infantum is a potentially fatal disease. To date there are no registered vaccines for disease prevention despite the fact that several vaccines are in ...