Browsing by Subject "catalysis"
Now showing items 1-20 of 20
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Asymmetric behavior of archaeal prolyl-tRNA synthetase
(2005)Archaeal prolyl-tRNA synthetases differ from their bacterial counterparts: they contain an additional domain (about 70 amino acids) appended to the carboxy-terminus and lack an editing domain inserted into the class II ... -
Biochemical and in silico identification of the active site and the catalytic mechanism of the circadian deadenylase HESPERIN
(2022)The 24-h molecular clock is based on the stability of rhythmically expressed transcripts. The shortening of the poly(A) tail of mRNAs is often the first and rate-limiting step that determines the lifespan of a mRNA and is ... -
Crude bio-glycerol aqueous phase reforming and hydrogenolysis over commercial SiO2Al2O3 nickel catalyst
(2016)In the present work, an one-pot Aqueous Phase Reforming (APR) and Aqueous Phase Hydrogenolysis (APH) of crude glycerol in a batch reactor containing commercial SiO2Al2O3 supported 65%Ni catalyst is performed. The effect ... -
Decoding the reproductive system of the olive fruit fly, Bactrocera oleae
(2021)In most diploid organisms, mating is a prerequisite for reproduction and, thus, critical to the maintenance of their population and the perpetuation of the species. Besides the importance of understanding the fundamentals ... -
Effect of Leguminosae family plant extracts and polyphenolic fractions on topoisomerase I-induced nicking of DNA
(2008)Topoisomerase I constitutes one of the enzymes playing crucial role in replication, transcription, recombination, chromosome condensation and maintenance of genome stability. Because it is an essential enzyme for vital ... -
Enhanced electrocatalytic overall water splitting over novel one-pot synthesized Ru–MoO3-x and Fe3O4–NiFe layered double hydroxide on Ni foam
(2021)Herein, two novel electrocatalysts are simultaneously grown on Ni foam (NF) through a one-step hydrothermal method. The as-prepared Ru–MoO3-x NF exhibits good performance for HER with low overpotentials of 12 mV at 10 mA ... -
Evidence for disulfide bonds in SR Protein Kinase 1 (SRPK1) that are required for activity and nuclear localization
(2017)Serine/arginine protein kinases (SRPKs) phosphorylate Arg/Ser dipeptide-containing proteins that play crucial roles in a broad spectrum of basic cellular processes. The existence of a large internal spacer sequence that ... -
A freestanding proofreading domain is required for protein synthesis quality control in Archaea
(2004)Threonyl-tRNA synthetase (ThrRS) participates in protein synthesis quality control by selectively editing the misacylated species Ser-tRNAThr. In bacteria and eukaryotes the editing function of ThrRS resides in a highly ... -
Genetic polymorphism of canine cytochrome P450 2D25 gene
(2004)Human CYP2D6 is involved in the metabolism of a number of drugs including neuroleptics, tricyclic antidepressants, β-adrenoreceptors antagonists and antiarrhythmic drugs. The corresponding canine CYP2D15 have shown similar ... -
A green approach for enhancing the electrocatalytic activity and stability of NiFe2O4/CB nanospheres towards hydrogen production
(2020)Among the exfoliation processes applied on layered materials, it is the first time to explore the ultrasonic exfoliation in water for improving the catalytic properties of NiFe2O4/CB (CB = carbon black) nanospheres towards ... -
Highly stable cathodes for proton exchange membrane fuel cells: Novel carbon supported Au@PtNiAu concave octahedral core-shell nanocatalyst
(2022)Despite the remarkable research efforts, the lack of ideal activity and state-of-the-art electrocatalysts remains a substantial challenge for the global application of fuel cell technology. Herein, is reported the synthesis ... -
Intermolecular latency regulates the essential C-terminal signal peptidase and sortase of the Porphyromonas gingivalis type-IX secretion system
(2021)Porphyromonas gingivalis is a keystone pathogen of the human dysbiotic oral microbiome that causes severe periodontitis. It employs a type-IX secretion system (T9SS) to shuttle proteins across the outer membrane (OM) for ... -
Lincomycin resistance gene lnu(D) in Streptococcus uberis
(2008)Streptococcus uberis UCN 42, isolated from a case of bovine mastitis, was intermediately resistant to lincomycin (MIC = 2 μg/ml) while remaining susceptible to clindamycin (MIC = 0.06 μg/ml) and erythromycin. A 1.1-kb SacI ... -
Metabolism of isovanillin by aldehyde oxidase, xanthine oxidase, aldehyde dehydrogenase and liver slices
(2005)Aromatic aldehydes are good substrates of aldehyde dehydrogenase activity but are relatively poor substrates of aldehyde oxidase and xanthine oxidase. However, the oxidation of xenobiotic-derived aromatic aldehydes by the ... -
Photocatalytic treatment of colored wastewater from medical laboratories: photodegradation of Nuclear Fast Red
(2016)The degradation and organic content reduction of Nuclear Fast Red (NFR, a counterstain reagent widely used in biochemical and biomedical laboratories) in aqueous solutions has been studied by heterogeneous photocatalytic ... -
Preparation and characterization of novel Niln2S4/UiO-66 photocatalysts for the efficient degradation of antibiotics in water
(2022)Photocatalysis is considered an economical, environmentally friendly, and effective technology for removing pollutants. The construction of Z-Scheme heterojunctions has been identified as one of the feasible solutions ... -
Protein phosphatase PPP3CA (calcineurin A) down-regulates hypoxia-inducible factor transcriptional activity
(2019)Hypoxia-inducible factors (HIF) are master regulators of the response to hypoxia. Although several kinases are known to modify their oxygen sensitive HIF-α subunits or affect indirectly their function, little is known about ... -
RNase P: A promising molecular target for the development of new drugs
(2004)RNase P is an ubiquitous and essential endonuclease in tRNA biogenesis, which generates the mature 5′-termini of tRNAs. RNase P activities have been identified in all three kingdoms of life (Bacteria, Archaea, Eukarya). ... -
Synthesis and Biological Evaluation of Novel 2-Substituted Analogues of (-)-Pentenomycin i
(2020)A library of novel 2-substituted derivatives of the antibiotic natural product pentenomycin I is presented. The new collection of analogues is divided in two main classes, 2-alkynyl- and 2-aryl- derivatives, which are ... -
Synthetic flavonoid derivatives targeting the glycogen phosphorylase inhibitor site: QM/MM-PBSA motivated synthesis of substituted 5,7-dihydroxyflavones, crystallography, in vitro kinetics and ex-vivo cellular experiments reveal novel potent inhibitors
(2020)Glycogen phosphorylase (GP) is an important target for the development of new anti-hyperglycaemic agents. Flavonoids are novel inhibitors of GP, but their mode of action is unspecific in terms of the GP binding sites ...