Browsing by Author "Labrou, M."
Now showing items 1-7 of 7
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Activity of Oxacillin versus That of Vancomycin against Oxacillin-Susceptible mecA-Positive Staphylococcus aureus Clinical Isolates Evaluated by Population Analyses, Time-Kill Assays, and a Murine Thigh Infection Model
Labrou, M.; Michail, G.; Ntokou, E.; Pittaras, T. E.; Pournaras, S.; Tsakris, A. (2012)We compared the activity of dicloxacillin with that of vancomycin against 15 oxacillin-susceptible, methicillin-resistant Staphylococcus aureus (OS-MRSA) clinical isolates. By population analyses, we found that 6 OS-MRSA ... -
Activity of Tigecycline in Combination with Colistin, Meropenem, Rifampin, or Gentamicin against KPC-Producing Enterobacteriaceae in a Murine Thigh Infection Model
Michail, G.; Labrou, M.; Pitiriga, V.; Manousaka, S.; Sakellaridis, N.; Tsakris, A.; Pournaras, S. (2013)Limited antimicrobials remain active for treating severe infections due to KPC-producing pathogens, and optimal regimens have not been established. In murine thigh infections caused by nine KPC-producing clinical strains ... -
Alterations of Deadenylase Expression in Acute Leukemias: Evidence for Poly(A)-Specific Ribonuclease as a Potential Biomarker
Maragozidis, P.; Karangeli, M.; Labrou, M.; Dimoulou, G.; Papaspyrou, K.; Salataj, E.; Pournaras, S.; Matsouka, P.; Gourgoulianis, K. I.; Balatsos, N. A. A. (2012)Background/Aims: The degradation of mRNA is a key process in the control of gene expression correlated to anomalous cell proliferation. The rate-limiting step of mRNA degradation is the removal of the poly(A) tail by ... -
Detection of mutations in the FemXAB protein family in oxacillin-susceptible mecA-positive Staphylococcus aureus clinical isolates
Giannouli, S.; Labrou, M.; Kyritsis, A.; Ikonomidis, A.; Pournaras, S.; Stathopoulos, C.; Tsakris, A. (2010)Methicillin-resistant Staphylococcus aureus (MRSA) strains that express the mecA gene but are oxacillin susceptible (OS-MRSA; oxacillin MIC < 2 mg/L) are increasingly reported. To gain molecular and functional insights on ... -
Differences in biofilm formation and virulence factors between clinical and fecal enterococcal isolates of human and animal origin
Tsikrikonis, G.; Maniatis, A. N.; Labrou, M.; Ntokou, E.; Michail, G.; Daponte, A.; Stathopoulos, C.; Tsakris, A.; Pournaras, S. (2012)The present study investigated the possible correlation between carriage of the virulence genes esp and fsrb, production of hemolysin and gelatinase and biofilm formation in human vs. animal enterococcal isolates. A ... -
In Vitro and In Vivo Evaluations of Oxacillin Efficiency against mecA-Positive Oxacillin-Susceptible Staphylococcus aureus
Ikonomidis, A.; Michail, G.; Vasdeki, A.; Labrou, M.; Karavasilis, V.; Stathopoulos, C.; Maniatis, A. N.; Pournaras, S. (2008)Community-type Staphylococcus aureus strains that are positive for mecA and PBP2a but appear phenotypically susceptible to oxacillin are increasingly reported worldwide. Four S. aureus clinical isolates carrying the mecA ... -
Intensive care unit dissemination of multiple clones of linezolid-resistant Enterococcus faecalis and Enterococcus faecium
Ntokou, E.; Stathopoulos, C.; Kristo, I.; Dimitroulia, E.; Labrou, M.; Vasdeki, A.; Makris, D.; Zakynthinos, E.; Tsakris, A.; Pournaras, S. (2012)Outbreaks caused by linezolid-resistant (LR) enterococci remain rare. We report the epidemiological and molecular characteristics of the multiclonal dissemination of LR enterococci in the intensive care unit (ICU) of a ...