Πλοήγηση ανά Θέμα "GENE"
Αποτελέσματα 41-60 από 81
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Increasing prevalence of high-level gentamicin resistance among enterococci isolated in Greece
(2001)High-level gentamicin-resistant enterococci (HLGRE) (MIC >512 mug/ml) were frequently recovered in the AHEPA University Hospital, Thessaloniki, Greece, during a 15-month period (67/158, 42.4%). PCR testing showed that ... -
Integration of High-Volume Molecular and Imaging Data for Composite Biomarker Discovery in the Study of Melanoma
(2014)In this work the effects of simple imputations are studied, regarding the integration of multimodal data originating from different patients. Two separate datasets of cutaneous melanoma are used, an image analysis (dermoscopy) ... -
The involvement of HER2 and p53 status in the regulation of telomerase in irradiated breast cancer cells
(2009)Cancer cell characteristics may play a pivotal role in the response to therapy by activating or deactivating different molecular pathways. In the present study, we investigated the implication of breast cancer cell features, ... -
Lack of association between the UDP-glucuronosyltransferase 1A1 (UGT1A1) gene polymorphism and the risk of benign prostatic hyperplasia in Caucasian men
(2013)Glucuronidation, mediated by the UDP-glucuronosyltransferase 1A1 (UGT1A1) enzyme, is an important metabolic process during which steroids are converted to more easily excreted compounds in steroid target tissues, such as ... -
Large Dissemination of VIM-2-Metallo-beta-Lactamase-Producing Pseudomonas aeruginosa Strains Causing Health Care-Associated Community-Onset Infections
(2009)During a 3-year period (May 2005 to April 2008), a series of 45 outpatients presented with community-onset urinary tract infections due to carbapenem-resistant Pseudomonas aeruginosa isolates. Forty of them had a history ... -
Loss of CCDC6 Affects Cell Cycle through Impaired Intra-S-Phase Checkpoint Control
(2012)In most cancers harboring Ccdc6 gene rearrangements, like papillary thyroid tumors or myeloproliferative disorders, the product of the normal allele is supposed to be functionally impaired or absent. To address the consequence ... -
Low expression of p27 protein combined with altered p53 and Rb/p16 expression status is associated with increased expression of cyclin A and cyclin B1 in diffuse large B-cell lymphomas
(2001)The expression of the cyclin-dependent kinase inhibitor (CDKI) p27 protein was investigated in relation to (1) the expression of the cell cycle regulators p53, Rb and p16 and (2) the proliferation profile as determined by ... -
Low-Density Lipoprotein Receptor-Related Protein 5 (LRP5) Expression in Human Osteoarthritic Chondrocytes
(2010)The aim of this study was to investigate the activation of the Wnt/beta-catenin pathway in osteoarthritis and the role of low-density lipoprotein receptor-related protein 5 (LRP5) in human osteoarthritic chondrocytes. The ... -
MBL2 Genotypes and Their Associations with MBL Levels and NICU Morbidity in a Cohort of Greek Neonates
(2015)The objective of this study was to assess the frequency of MBL2 genotypes and their associations with MBL levels and various morbidities of a neonatal intensive care unit (NICU). One hundred and thirty-four (134) NICU (83 ... -
Metabolic and functional diversity of saponins, biosynthetic intermediates and semi-synthetic derivatives
(2014)Saponins are widely distributed plant natural products with vast structural and functional diversity. They are typically composed of a hydrophobic aglycone, which is extensively decorated with functional groups prior to ... -
Methylation status of RASSF1A in patients with chronic myeloid leukemia
(2009)RASSF1A, a key cell cycle related gene, is expressed in all hematopoietic cells, it is implicated in ras signaling pathway and its promoter hypermethylation is observed in a wide variety of solid tumors. Till now, RASSF1A ... -
miRNA Regulons Associated with Synaptic Function
(2012)Differential RNA localization and local protein synthesis regulate synapse function and plasticity in neurons. MicroRNAs are a conserved class of regulatory RNAs that control mRNA stability and translation in tissues. They ... -
Molecular characterization and biological response to respiration inhibitors of Pyricularia isolates from ctenanthe and rice plants
(2005)The molecular profile and the biological response of isolates of Pyricularia oryzae Cavara obtained from ctenanthe to two strobilurins (azoxystrobin, kresoxim-methyl) and the phenylpyridinamine fungicide fluazinarn were ... -
Molecular cloning and biochemical characterization of VIM-12, a novel hybrid VIM-1/VIM-2 metallo-beta-lactamase from a Klebsiella pneumoniae clinical isolate, reveal atypical substrate specificity
(2007)Metallo-beta-lactamases (MBLs) are considered an emerging family of Zn2+-dependent enzymes that significantly contribute to the resistance of many nosocomial pathogens against beta-lactam antimicrobials. Since these ... -
Molecular cloning and sequence of gilthead sea bream (Sparus aurata) alpha-skeletal actin: tissue and developmental expression
(2001)In the present study, the Sparus aurata alpha -skeletal actin was cloned from a mixed larvae complementary DNA library. The clone isolated was 1523 bp long with an open reading frame of 1134 bp coding for a 377-amino acid ... -
Molecular cloning and sequence of Sparus aurata skeletal myosin light chains expressed in white muscle: developmental expression and thyroid regulation
(2001)Two full-length cDNA clones encoding the skeletal myosin light chain 2 (MLC2; 1452 bp) and myosin light chain 3 (MLC3; 972 bp) were isolated from a cDNA library prepared from gilthead sea bream Sparus aurata larvae. The ... -
Molecular detection of the entomopathogenic bacterium Pseudomonas entomophila using PCR
(2010)Aims: To develop a specific, fast and simple molecular method useful to detect the entomopathogenic bacterium Pseudomonas entomophila. Methods and Results: The use of bioinformatics tools allowed the identification of ... -
New aspects upon the classification of Staphylococcus intermedius
(2010)In 1976, Staphylococcus intermedius was first described as being a new species isolated from pigeons, dogs, mink and horses. Until recently, the majority of coagulase-positive staphylococci originating from animals such ... -
New Sequence Variants in HLA Class II/III Region Associated with Susceptibility to Knee Osteoarthritis Identified by Genome-Wide Association Study
(2010)Osteoarthritis (OA) is a common disease that has a definite genetic component. Only a few OA susceptibility genes that have definite functional evidence and replication of association have been reported, however. Through ... -
A new set of 16S rRNA universal primers for identification of animal species
(2014)In this study, bioinformatics were used to specifically design universal primers within 16S rRNA gene according to the following criteria: the priming sites needed to be sufficiently conserved to permit a reliable amplification ...