dc.creator | Moschos M.M., Moustafa G.A., Lavaris A., Damaskos C., Laios K., Karathanou E., Ladas D.S., Asproudis I., Garmpis N., Kalogeropoulos C. | en |
dc.date.accessioned | 2023-01-31T09:01:31Z | |
dc.date.available | 2023-01-31T09:01:31Z | |
dc.date.issued | 2018 | |
dc.identifier | 10.21873/anticanres.12562 | |
dc.identifier.issn | 02507005 | |
dc.identifier.uri | http://hdl.handle.net/11615/76763 | |
dc.description.abstract | Aim: To determine depression in patients with choroidal melanoma (CM) treated with proton beam radiotherapy. Patients and Methods: This was a cross-sectional study including 50 patients with CM (50% males, mean age=49.88±6.34 years) and 46 age- and sex-matched healthy controls (52% males, mean age=48.60±8.05 years). Participants completed the Patient Health Questionnaire-9 (PHQ-9) and the Zung Self-Rating Depression Scale (SDS) questionnaires. Results: There was a considerable difference in visual acuity as logarithm of the minimum angle of resolution (logMAR) between the patient and control groups (1.16±0.97 and 0.04±0.05 logMAR, respectively, p<0.0001). Both PHQ-9 and SDS scores differed significantly between the two groups (10.18±4.68 and 8.07±4.90, p=0.04; and 47.94±12.56 and 39.91±8.80, p=0.004, respectively). Scores appeared to be positively correlated with logMAR visual acuity (Spearman rho=0.700, p<0.0001 for PHQ-9; and 0.767, p<0.0001 for SDS), and they were also correlated to each other (Spearman rho=0.759, p<0.0001). Conclusion: Patients with CM having undergone proton beam therapy seem to be more depressed compared to a sample of healthy individuals, and the level of depression is correlated with their visual acuity. © 2018 International Institute of Anticancer Research. All rights reserved. | en |
dc.language.iso | en | en |
dc.source | Anticancer Research | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85046504082&doi=10.21873%2fanticanres.12562&partnerID=40&md5=877a294734c1ddd6008b674a8dd34913 | |
dc.subject | adult | en |
dc.subject | Article | en |
dc.subject | best corrected visual acuity | en |
dc.subject | cancer radiotherapy | en |
dc.subject | choroid melanoma | en |
dc.subject | clinical article | en |
dc.subject | controlled study | en |
dc.subject | cross-sectional study | en |
dc.subject | depression | en |
dc.subject | disease severity | en |
dc.subject | female | en |
dc.subject | human | en |
dc.subject | male | en |
dc.subject | Patient Health Questionnaire 9 | en |
dc.subject | priority journal | en |
dc.subject | proton therapy | en |
dc.subject | Zung Self Rating Depression Scale | en |
dc.subject | aged | en |
dc.subject | choroid tumor | en |
dc.subject | depression | en |
dc.subject | melanoma | en |
dc.subject | middle aged | en |
dc.subject | proton therapy | en |
dc.subject | psychology | en |
dc.subject | uvea tumor | en |
dc.subject | Adult | en |
dc.subject | Aged | en |
dc.subject | Choroid Neoplasms | en |
dc.subject | Cross-Sectional Studies | en |
dc.subject | Depression | en |
dc.subject | Female | en |
dc.subject | Humans | en |
dc.subject | Male | en |
dc.subject | Melanoma | en |
dc.subject | Middle Aged | en |
dc.subject | Proton Therapy | en |
dc.subject | Uveal Neoplasms | en |
dc.subject | International Institute of Anticancer Research | en |
dc.title | Depression in choroidal melanoma patients treated with proton beam radiotherapy | en |
dc.type | journalArticle | en |