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Risk evaluation of vitamin D insufficiency or deficiency in children using simple scores: The Healthy Growth Study
dc.creator | Moschonis G., Androutsos O., Hulshof T., Sarapis K., Dracopoulou M., Chrousos G.P., Manios Y. | en |
dc.date.accessioned | 2023-01-31T09:01:27Z | |
dc.date.available | 2023-01-31T09:01:27Z | |
dc.date.issued | 2021 | |
dc.identifier | 10.1016/j.nutres.2020.12.021 | |
dc.identifier.issn | 02715317 | |
dc.identifier.uri | http://hdl.handle.net/11615/76758 | |
dc.description.abstract | Although identification of population groups at high risk for low vitamin D status is of public health importance,there are no risk prediction tools available for children in Southern Europe that can cover this need. The present study aimed to develop and validate 2 simple scores that evaluate the risk for vitamin D insufficiency or deficiency in children. A cross-sectional epidemiological study was conducted among 2280 schoolchildren (9–13-year-old) living in Greece. The total sample was randomly divided into 2 subsamples of 1524 and 756 children, used in the development and validation of the 2 scores, respectively. Multivariate logistic regression analyses were used to develop the 2 risk evaluation scores, while receiver operating characteristic curves were employed to identify the optimal “points of change” for each risk score, upon which vitamin D insufficiency and deficiency is diagnosed with the highest possible sensitivity and specificity. The components of the 2 risk evaluation scores included children's age, gender, region of residence, screen-time, body weight status, maternal education, and season. The increase in each score by 1 unit elevated the likelihood for vitamin D insufficiency and deficiency by 31% and 28%, respectively. The receiver operating characteristic curves showed that the optimal “points of change” for each risk score, upon which vitamin D insufficiency or deficiency is diagnosed with the highest possible sensitivity and specificity were 8.5 and 12.5, respectively. In conclusion, this study developed 2 simple scores that evaluate the risk for vitamin D insufficiency or deficiency in children living in Greece. However, more studies are required for these scores to be validated in other populations of children from different countries. © 2020 | en |
dc.language.iso | en | en |
dc.source | Nutrition Research | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102620182&doi=10.1016%2fj.nutres.2020.12.021&partnerID=40&md5=209f3fa3e6efcd59d9f8a5bcce3aabf1 | |
dc.subject | age | en |
dc.subject | Article | en |
dc.subject | body weight | en |
dc.subject | child | en |
dc.subject | cohort analysis | en |
dc.subject | controlled study | en |
dc.subject | cross-sectional study | en |
dc.subject | disease assessment | en |
dc.subject | educational status | en |
dc.subject | epidemiological data | en |
dc.subject | female | en |
dc.subject | gender | en |
dc.subject | Greece | en |
dc.subject | human | en |
dc.subject | major clinical study | en |
dc.subject | male | en |
dc.subject | maternal attitude | en |
dc.subject | program development | en |
dc.subject | receiver operating characteristic | en |
dc.subject | residential area | en |
dc.subject | risk assessment | en |
dc.subject | school child | en |
dc.subject | screen time | en |
dc.subject | seasonal variation | en |
dc.subject | sensitivity and specificity | en |
dc.subject | study design | en |
dc.subject | validation process | en |
dc.subject | vitamin D deficiency | en |
dc.subject | adolescent | en |
dc.subject | blood | en |
dc.subject | bone development | en |
dc.subject | physiology | en |
dc.subject | risk factor | en |
dc.subject | season | en |
dc.subject | socioeconomics | en |
dc.subject | vitamin D deficiency | en |
dc.subject | 25-hydroxyvitamin D | en |
dc.subject | vitamin D | en |
dc.subject | Adolescent | en |
dc.subject | Bone Development | en |
dc.subject | Child | en |
dc.subject | Female | en |
dc.subject | Greece | en |
dc.subject | Humans | en |
dc.subject | Male | en |
dc.subject | Risk Factors | en |
dc.subject | ROC Curve | en |
dc.subject | Screen Time | en |
dc.subject | Seasons | en |
dc.subject | Socioeconomic Factors | en |
dc.subject | Vitamin D | en |
dc.subject | Vitamin D Deficiency | en |
dc.subject | Elsevier Inc. | en |
dc.title | Risk evaluation of vitamin D insufficiency or deficiency in children using simple scores: The Healthy Growth Study | en |
dc.type | journalArticle | en |
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