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dc.creatorMakris D., Leroy S., Pradelli J., Benzaquen J., Guenard H., Perotin J.-M., Zakynthinos S., Zakynthinos E., Deslee G., Marquette C.H.en
dc.date.accessioned2023-01-31T08:56:00Z
dc.date.available2023-01-31T08:56:00Z
dc.date.issued2018
dc.identifier10.1136/thoraxjnl-2017-210118
dc.identifier.issn00406376
dc.identifier.urihttp://hdl.handle.net/11615/76139
dc.description.abstractWe assessed the relationships between changes in lung compliance, lung volumes and dynamic hyperinflation in patients with emphysema who underwent bronchoscopic treatment with nitinol coils (coil treatment) (n=11) or received usual care (UC) (n=11). Compared with UC, coil treatment resulted in decreased dynamic lung compliance (CLdyn) (p=0.03) and increased endurance time (p=0.010). The change in CLdyn was associated with significant improvement in FEV 1 and FVC, with reduction in residual volume and intrinsic positive end-expiratory pressure, and with increased inspiratory capacity at rest/and at exercise. The increase in end-expiratory lung volume (EELV) during exercise (EELVdyn-ch =EELVisotime EELVrest) demonstrated significant attenuation after coil treatment (p=0.02). © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.en
dc.language.isoenen
dc.sourceThoraxen
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85046650139&doi=10.1136%2fthoraxjnl-2017-210118&partnerID=40&md5=6424bd677287bf98d96b17378e304d8d
dc.subjectnitinolen
dc.subjectalloyen
dc.subjectArticleen
dc.subjectbronchoscopyen
dc.subjectclinical articleen
dc.subjectcontrolled studyen
dc.subjectdisease severityen
dc.subjectemphysemaen
dc.subjectend expiratory lung volumeen
dc.subjectenduranceen
dc.subjectexerciseen
dc.subjectforced expiratory volumeen
dc.subjectforced vital capacityen
dc.subjecthumanen
dc.subjecthyperinflationen
dc.subjectlung complianceen
dc.subjectlung mechanicsen
dc.subjectlung resectionen
dc.subjectlung volumeen
dc.subjectpositive end expiratory pressureen
dc.subjectpriority journalen
dc.subjectresidual volumeen
dc.subjecttreatment outcomeen
dc.subjectadulten
dc.subjectageden
dc.subjectbreathing mechanicsen
dc.subjectfemaleen
dc.subjectlung emphysemaen
dc.subjectlung resectionen
dc.subjectmiddle ageden
dc.subjectpathophysiologyen
dc.subjectphysiologyen
dc.subjectproceduresen
dc.subjectprospective studyen
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAlloysen
dc.subjectBronchoscopyen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectLung Complianceen
dc.subjectLung Volume Measurementsen
dc.subjectMiddle Ageden
dc.subjectPhysical Enduranceen
dc.subjectPneumonectomyen
dc.subjectProspective Studiesen
dc.subjectPulmonary Emphysemaen
dc.subjectRespiratory Mechanicsen
dc.subjectBMJ Publishing Groupen
dc.titleChanges in dynamic lung mechanics after lung volume reduction coil treatment of severe emphysemaen
dc.typejournalArticleen


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