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Ursodeoxycholic Acid in the Prevention of Gallstone Formation After Bariatric Surgery: an Updated Systematic Review and Meta-analysis

dc.creatorMagouliotis D.E., Tasiopoulou V.S., Svokos A.A., Svokos K.A., Chatedaki C., Sioka E., Zacharoulis D.en
dc.date.accessioned2023-01-31T08:55:47Z
dc.date.available2023-01-31T08:55:47Z
dc.date.issued2017
dc.identifier10.1007/s11695-017-2924-y
dc.identifier.issn09608923
dc.identifier.urihttp://hdl.handle.net/11615/76095
dc.description.abstractWe aim to review the available literature on obese patients treated with ursodeoxycholic acid (UDCA) in order to prevent gallstone formation after bariatric surgery. A systematic literature search was performed in PubMed, Cochrane library, and Scopus databases, in accordance with the PRISMA guidelines. Eight studies met the inclusion criteria incorporating 1355 patients. Random-effects meta-analysis showed a lower incidence of gallstone formation in patients taking UDCA. Subgroup analysis reported fewer cases of gallstone disease in the UDCA group in relation to different bariatric procedures, doses of administered UDCA, and time from bariatric surgery. Adverse events were similar in both groups. Fewer patients required cholecystectomy in UDCA group. No deaths were reported. The administration of UDCA after bariatric surgery seems to prevent gallstone formation. © 2017, Springer Science+Business Media, LLC.en
dc.language.isoenen
dc.sourceObesity Surgeryen
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85028992104&doi=10.1007%2fs11695-017-2924-y&partnerID=40&md5=6dc7723a35193662afdffdd22f89e1d8
dc.subjectursodeoxycholic aciden
dc.subjectursodeoxycholic aciden
dc.subjectbariatric surgeryen
dc.subjectcholecystectomyen
dc.subjectconstipationen
dc.subjectdrug hypersensitivityen
dc.subjectgallstone formationen
dc.subjecthumanen
dc.subjectincidenceen
dc.subjectmedication complianceen
dc.subjectmeta analysisen
dc.subjectnauseaen
dc.subjectpatient complianceen
dc.subjectpriority journalen
dc.subjectReviewen
dc.subjectsystematic reviewen
dc.subjecttime to treatmenten
dc.subjectvomitingen
dc.subjectweight reductionen
dc.subjectadulten
dc.subjectbariatric surgeryen
dc.subjectchemoprophylaxisen
dc.subjectgallstoneen
dc.subjectmorbid obesityen
dc.subjectproceduresen
dc.subjectrehabilitationen
dc.subjectstatistics and numerical dataen
dc.subjectAdulten
dc.subjectBariatric Surgeryen
dc.subjectChemopreventionen
dc.subjectCholecystectomyen
dc.subjectGallstonesen
dc.subjectHumansen
dc.subjectObesity, Morbiden
dc.subjectUrsodeoxycholic Aciden
dc.subjectSpringer New York LLCen
dc.titleUrsodeoxycholic Acid in the Prevention of Gallstone Formation After Bariatric Surgery: an Updated Systematic Review and Meta-analysisen
dc.typeotheren


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