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Pesticide exposure and cognitive function: Results from the Hellenic Longitudinal Investigation of Aging and Diet (HELIAD)

dc.creatorDardiotis E., Siokas V., Moza S., Kosmidis M.H., Vogiatzi C., Aloizou A.-M., Geronikola N., Ntanasi E., Zalonis I., Yannakoulia M., Scarmeas N., Hadjigeorgiou G.M.en
dc.date.accessioned2023-01-31T07:51:03Z
dc.date.available2023-01-31T07:51:03Z
dc.date.issued2019
dc.identifier10.1016/j.envres.2019.108632
dc.identifier.issn00139351
dc.identifier.urihttp://hdl.handle.net/11615/73095
dc.description.abstractBackground: Results from studies to date, regarding the role of chronic pesticide exposure on cognitive function remain contradictory. Objective: To investigate the relationship between self-reported pesticide exposure and cognitive function. Methods: Data from a population-based cohort study of older adults (HEllenic Longitudinal Investigation of Aging and Diet) in Greece was used. Pesticide exposure classification was based on 1) living in areas that were being sprayed; 2) application of spray insecticides/pesticides in their gardens; and 3) occupational application of sprays. Associations between z-scores of cognitive performance and self-reported pesticide exposure were examined with linear regression analyses. Adjusted models were applied, for all analyses. Results: Non-demented individuals who reported that they had been living in areas near sprayed fields, had poorer neuropsychological performance, compared to those who had never lived in such areas. Sub-analyses revealed poorer performance in language, executive and visual-spatial functioning, and attention. These associations remained after a sensitivity analysis excluding subjects with mild cognitive impairment. Conclusion: Self-reported exposure to pesticides was negatively associated with cognitive performance. © 2019 Elsevier Inc.en
dc.language.isoenen
dc.sourceEnvironmental Researchen
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85070630357&doi=10.1016%2fj.envres.2019.108632&partnerID=40&md5=a45c614143b7ef5bc4c67d47abfc1e7a
dc.subjectpesticideen
dc.subjectpesticideen
dc.subjectagingen
dc.subjectcognitionen
dc.subjectdietary intakeen
dc.subjectenvironmental risken
dc.subjectmental healthen
dc.subjectpesticide residueen
dc.subjectpollution exposureen
dc.subjectsensitivity analysisen
dc.subjectageden
dc.subjectArticleen
dc.subjectcognitionen
dc.subjectcohort analysisen
dc.subjectenvironmental exposureen
dc.subjectfemaleen
dc.subjectGreeceen
dc.subjecthumanen
dc.subjectlanguageen
dc.subjectlongitudinal studyen
dc.subjectmajor clinical studyen
dc.subjectmaleen
dc.subjectmental functionen
dc.subjectmental performanceen
dc.subjectmild cognitive impairmenten
dc.subjectneuropsychological testen
dc.subjectoccupational exposureen
dc.subjectpriority journalen
dc.subjectsensitivity analysisen
dc.subjectadverse eventen
dc.subjectdieten
dc.subjectland useen
dc.subjectvery elderlyen
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectCognitionen
dc.subjectCohort Studiesen
dc.subjectDieten
dc.subjectEnvironmental Exposureen
dc.subjectFemaleen
dc.subjectGardensen
dc.subjectGreeceen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectNeuropsychological Testsen
dc.subjectOccupational Exposureen
dc.subjectPesticidesen
dc.subjectAcademic Press Inc.en
dc.titlePesticide exposure and cognitive function: Results from the Hellenic Longitudinal Investigation of Aging and Diet (HELIAD)en
dc.typejournalArticleen


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