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dc.creatorChouzouris T.M., Dovolou E., Georgoulias P., Rekkas A., Dafopoulos K., Athanasiou L., Fthenakis G.C., Amiridis G.S.en
dc.date.accessioned2023-01-31T07:46:00Z
dc.date.available2023-01-31T07:46:00Z
dc.date.issued2018
dc.identifier10.1016/j.theriogenology.2017.10.011
dc.identifier.issn0093691X
dc.identifier.urihttp://hdl.handle.net/11615/72831
dc.description.abstractThe aims of this study were: to compare total ghrelin concentration throughout pregnancy between lactating cows and heifers, and to study the response to acute feed restriction in pregnant or non-pregnant heifers. Blood samples were collected each month of pregnancy from cows (n = 5) and heifers (n = 5) and analyzed for total ghrelin concentration. Compared to pre-conception values, ghrelin concentrations tended to be greater during 3rd month of pregnancy in heifers, whereas they were higher in the 7th, 8th and 9th months in lactating cows, but no difference was detected between lactating cows and heifers. In experiment two, pregnant (n = 4) and non-pregnant (n = 4) heifers were fasted for 24 h. Blood samples were collected 0, 4, 8, 12, 16 and 24 h of fasting and were assayed for, insulin, glucose, cortisol, BHBA and NEFA concentrations, and at time points 0, 8, 16 and 24 for total ghrelin determination. Compared to satiety, ghrelin concentrations were higher at 8th, 16th and 24th hour of fasting in pregnant and at 8th hour in non-pregnant animals, but no difference was detected between pregnant and non-pregnant heifers. Pregnant heifers had lower glucose concentrations than non-pregnant ones. Insulin concentrations were reduced at 4 and 8 h of fasting in pregnant heifers, and stayed unaffected in non-pregnant ones. Cortisol concentrations increased after 4th hour and remained elevated throughout the sampling period in pregnant heifers, while they increased at 24th h in non-pregnant animals. Here, we provide evidence that total ghrelin concentrations rise in response to feed restriction. Albeit no group effect was evident, our results imply that a) during the last trimester of pregnancy total ghrelin is secreted in different pattern between lactating cows and heifers, b) pregnant animals are more responsive than non-pregnant ones to hunger induced stress. © 2017en
dc.language.isoenen
dc.sourceTheriogenologyen
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85031997811&doi=10.1016%2fj.theriogenology.2017.10.011&partnerID=40&md5=2a41b1e2e0f4ad2d3ef47dd1c62e98dd
dc.subjectghrelinen
dc.subjectanimalen
dc.subjectanimal fooden
dc.subjectblooden
dc.subjectbovineen
dc.subjectbreedingen
dc.subjectclinical trialen
dc.subjectenergy metabolismen
dc.subjectfemaleen
dc.subjectfood deprivationen
dc.subjectlactationen
dc.subjectmetabolismen
dc.subjectphysiologyen
dc.subjectpregnancyen
dc.subjectAnimal Feeden
dc.subjectAnimalsen
dc.subjectCattleen
dc.subjectEnergy Metabolismen
dc.subjectFemaleen
dc.subjectFood Deprivationen
dc.subjectGhrelinen
dc.subjectLactationen
dc.subjectPregnancyen
dc.subjectPregnancy, Animalen
dc.subjectElsevier Inc.en
dc.titleEffects of pregnancy and short-lasting acute feed restriction on total ghrelin concentration and metabolic parameters in dairy cattleen
dc.typejournalArticleen


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