Acute and Sub-Lethal Toxicity of Aluminum on Developing Zebrafish Embryos

Abstract

Acute toxicity and sub-lethal developmental aluminum (Al) toxicity on zebrafish embryos were determined in the present work. Four-hour postfertilization zebrafish embryos were randomly divided into three experimental groups and a control. The developing embryos were exposed to 500, 50, and 0.05 mg l−1 Al2(SO4)3 solution for 96 h postfertilization. Exposure to Al resulted in delayed embryonic development and hatching and low levels of survival. The magnitude of the effects increased with increasing concentrations of Al. Compared to post-hatching stages, the magnitude of toxicity was higher in the pre-hatching embryonic stages of development. © 2021, The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG.