Όλο το DSpace

Εμφάνιση απλής εγγραφής

Mediterranean diet and risk for dementia and cognitive decline in a Mediterranean population

dc.creatorCharisis S., Ntanasi E., Yannakoulia M., Anastasiou C.A., Kosmidis M.H., Dardiotis E., Hadjigeorgiou G., Sakka P., Scarmeas N.en
dc.date.accessioned2023-01-31T07:43:17Z
dc.date.available2023-01-31T07:43:17Z
dc.date.issued2021
dc.identifier10.1111/jgs.17072
dc.identifier.issn00028614
dc.identifier.urihttp://hdl.handle.net/11615/72538
dc.description.abstractBackground: Current evidence suggests that nutrition in general and specific dietary patterns in particular, such as the Mediterranean type diet (MeDi), can be employed as potential preventive strategies against the development of dementia and cognitive decline. However, longitudinal data exploring the applicability of these findings in populations of Mediterranean origin are limited. The aim of the present study was to explore the potential relationships of MeDi adherence with dementia incidence rates and cognitive change over time in a traditional Mediterranean population, characterized by a lifelong exposure to Mediterranean eating habits and lifestyle. Methods: The sample consisted of 1046 non-demented individuals over the age of 64 (mean age = 73.1; SD = 5.0), with available baseline dietary information and longitudinal follow-up. Diagnosis of dementia was made by a full clinical and neuropsychological evaluation, while cognitive performance was assessed according to five cognitive domains (memory, language, attention-speed, executive functioning, visuospatial perception) and a global cognitive score. Adherence to MeDi was evaluated by an a priori score (range 0–55), derived from a detailed food frequency questionnaire. Results: A total of 62 incident dementia cases occurred during a mean (SD) of 3.1 (0.9) years of follow-up. Individuals in the highest MeDi quartile (highest adherence to MeDi) had a 72% lower risk for development of dementia, compared to those in the lowest one (p = 0.013). In addition, analysis of cognitive performance as a function of MeDi score revealed that the biennial cognitive benefit of a 10-unit increase in MeDi score offsets the cognitive decline associated with 1 year of cognitive aging. Conclusion: In the present study, higher adherence to MeDi was associated with a reduced risk for dementia and cognitive decline in a traditional Mediterranean population. © 2021 The American Geriatrics Societyen
dc.language.isoenen
dc.sourceJournal of the American Geriatrics Societyen
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85102628420&doi=10.1111%2fjgs.17072&partnerID=40&md5=6aea20e007c70b0415397c188ce8267a
dc.subjectageden
dc.subjectAlzheimer diseaseen
dc.subjectArticleen
dc.subjectattentionen
dc.subjectclinical evaluationen
dc.subjectcognitionen
dc.subjectcognitive agingen
dc.subjectcognitive defecten
dc.subjectcohort analysisen
dc.subjectcontrolled studyen
dc.subjectdementiaen
dc.subjectdepth perceptionen
dc.subjectdietary complianceen
dc.subjecteating habiten
dc.subjectexecutive functionen
dc.subjectfemaleen
dc.subjectfollow upen
dc.subjectfood frequency questionnaireen
dc.subjecthumanen
dc.subjectincidenceen
dc.subjectlanguageen
dc.subjectlifestyleen
dc.subjectlongitudinal studyen
dc.subjectlow risk populationen
dc.subjectmajor clinical studyen
dc.subjectmaleen
dc.subjectMediterranean dieten
dc.subjectmemoryen
dc.subjectneuropsychological testen
dc.subjectobservational studyen
dc.subjectpopulation researchen
dc.subjectprospective studyen
dc.subjectrisk reductionen
dc.subjectcognitive defecten
dc.subjectdementiaen
dc.subjectGreeceen
dc.subjectrisk factoren
dc.subjectAgeden
dc.subjectCognitive Dysfunctionen
dc.subjectDementiaen
dc.subjectDiet, Mediterraneanen
dc.subjectFemaleen
dc.subjectGreeceen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectNeuropsychological Testsen
dc.subjectRisk Factorsen
dc.subjectJohn Wiley and Sons Incen
dc.titleMediterranean diet and risk for dementia and cognitive decline in a Mediterranean populationen
dc.typejournalArticleen


Αρχεία σε αυτό το τεκμήριο

ΑρχείαΜέγεθοςΤύποςΠροβολή

Δεν υπάρχουν αρχεία που να σχετίζονται με αυτό το τεκμήριο.

Αυτό το τεκμήριο εμφανίζεται στις ακόλουθες συλλογές

Εμφάνιση απλής εγγραφής