Breast radiotherapy and early adverse cardiac effects. The role of serum biomarkers and strain echocardiography
dc.creator | Gkantaifi A., Papadopoulos C., Spyropoulou D., Toumpourleka M., Iliadis G., Kardamakis D., Nikolaou M., Tsoukalas N., Kyrgias G., Tolia M. | en |
dc.date.accessioned | 2023-01-31T07:42:40Z | |
dc.date.available | 2023-01-31T07:42:40Z | |
dc.date.issued | 2019 | |
dc.identifier | 10.21873/anticanres.13272 | |
dc.identifier.issn | 02507005 | |
dc.identifier.uri | http://hdl.handle.net/11615/72445 | |
dc.description.abstract | Breast cancer radiotherapy has a clear benefit for both long-term survival and local recurrence rate. However, there is still much concern about the early radiation-induced heart toxicity. This article aimed to clarify the impact of certain cardiac biomarkers and strain echocardiographic imaging on the detection of early cardiac dysfunction. Several studies that reported changes in either echocardiographic and/or serum levels measurements after breast radiotherapy were searched. Despite the established role of cardiac biomarkers to predict late cardiotoxicity after radiotherapy, data concerning early cardiac damage are still lacking. Furthermore, although strain echocardiography represents a specific tool for the detection of cardiac morbidity in certain diseases, much interest concerns its role in the prediction of early heart failure after radiotherapy. Identification of new tools for the detection of early cardiotoxicity after breast radiotherapy may minimize the side-effects of therapeutic modalities in the clinical setting. © 2019 International Institute of Anticancer Research. All rights reserved. | en |
dc.language.iso | en | en |
dc.source | Anticancer Research | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064496950&doi=10.21873%2fanticanres.13272&partnerID=40&md5=b88d289480ad99ec19431774c73f45fa | |
dc.subject | acute phase protein | en |
dc.subject | biological marker | en |
dc.subject | brain natriuretic peptide | en |
dc.subject | C reactive protein | en |
dc.subject | interleukin 1 | en |
dc.subject | interleukin 6 | en |
dc.subject | natriuretic factor | en |
dc.subject | troponin T | en |
dc.subject | tumor necrosis factor | en |
dc.subject | biological marker | en |
dc.subject | breast cancer | en |
dc.subject | breast radiotherapy | en |
dc.subject | cancer radiotherapy | en |
dc.subject | cardiotoxicity | en |
dc.subject | circulation | en |
dc.subject | clinical assessment | en |
dc.subject | echocardiography | en |
dc.subject | heart failure | en |
dc.subject | heart injury | en |
dc.subject | human | en |
dc.subject | meta analysis | en |
dc.subject | morbidity | en |
dc.subject | priority journal | en |
dc.subject | protein blood level | en |
dc.subject | radiation dose | en |
dc.subject | radiation injury | en |
dc.subject | radiation response | en |
dc.subject | randomized controlled trial (topic) | en |
dc.subject | Review | en |
dc.subject | speckle tracking echocardiography | en |
dc.subject | systematic review | en |
dc.subject | animal | en |
dc.subject | blood | en |
dc.subject | breast tumor | en |
dc.subject | cardiotoxicity | en |
dc.subject | diagnostic imaging | en |
dc.subject | echocardiography | en |
dc.subject | female | en |
dc.subject | heart | en |
dc.subject | heart disease | en |
dc.subject | pathophysiology | en |
dc.subject | predictive value | en |
dc.subject | procedures | en |
dc.subject | radiation injury | en |
dc.subject | radiation response | en |
dc.subject | risk factor | en |
dc.subject | Animals | en |
dc.subject | Biomarkers | en |
dc.subject | Breast Neoplasms | en |
dc.subject | Cardiotoxicity | en |
dc.subject | Echocardiography | en |
dc.subject | Female | en |
dc.subject | Heart | en |
dc.subject | Heart Diseases | en |
dc.subject | Humans | en |
dc.subject | Predictive Value of Tests | en |
dc.subject | Radiation Injuries | en |
dc.subject | Radiotherapy | en |
dc.subject | Risk Factors | en |
dc.subject | International Institute of Anticancer Research | en |
dc.title | Breast radiotherapy and early adverse cardiac effects. The role of serum biomarkers and strain echocardiography | en |
dc.type | other | en |
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