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Microbiome in multiple sclerosis; where are we, what we know and do not know

dc.creatorBoziki M.K., Kesidou E., Theotokis P., Mentis A.-F.A., Karafoulidou E., Melnikov M., Sviridova A., Rogovski V., Boyko A., Grigoriadis N.en
dc.date.accessioned2023-01-31T07:40:22Z
dc.date.available2023-01-31T07:40:22Z
dc.date.issued2020
dc.identifier10.3390/brainsci10040234
dc.identifier.issn20763425
dc.identifier.urihttp://hdl.handle.net/11615/72073
dc.description.abstractAn increase of multiple sclerosis (MS) incidence has been reported during the last decade, and this may be connected to environmental factors. This review article aims to encapsulate the current advances targeting the study of the gut–brain axis, which mediates the communication between the central nervous system and the gut microbiome. Clinical data arising from many research studies, which have assessed the effects of administered disease-modifying treatments in MS patients to the gut microbiome, are also recapitulated. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.en
dc.language.isoenen
dc.sourceBrain Sciencesen
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85084051878&doi=10.3390%2fbrainsci10040234&partnerID=40&md5=adbd734d17ece9cede5d462226a54d3d
dc.subjectalemtuzumaben
dc.subjectbrain derived neurotrophic factoren
dc.subjectfingolimoden
dc.subjectfumaric acid dimethyl esteren
dc.subjectgamma interferonen
dc.subjectglatirameren
dc.subjectgranzyme Ben
dc.subjectHLA DRB1 antigenen
dc.subjectinterleukin 10en
dc.subjectinterleukin 13en
dc.subjectinterleukin 17en
dc.subjectinterleukin 2en
dc.subjectinterleukin 27en
dc.subjectinterleukin 4en
dc.subjectinterleukin 6en
dc.subjectleptinen
dc.subjectmyelin oligodendrocyte glycoproteinen
dc.subjectmyeloid differentiation factor 88en
dc.subjectnatalizumaben
dc.subjectretinoic aciden
dc.subjectSTAT5 proteinen
dc.subjectsyndecan 1en
dc.subjectteriflunomideen
dc.subjecttransforming growth factor betaen
dc.subjecttransforming growth factor beta1en
dc.subjecttumor necrosis factoren
dc.subjectvitamin Den
dc.subjectActinobacteriaen
dc.subjectautoimmunityen
dc.subjectBacteroides fragilisen
dc.subjectblood brain barrieren
dc.subjectchronic lymphatic leukemiaen
dc.subjectClostridialesen
dc.subjectcytokine productionen
dc.subjectdendritic cellen
dc.subjectdiet supplementationen
dc.subjectenvironmental factoren
dc.subjectExpanded Disability Status Scaleen
dc.subjectFaecalibacteriumen
dc.subjectfecal microbiota transplantationen
dc.subjectFirmicutesen
dc.subjecthumanen
dc.subjectimmune responseen
dc.subjectimmunological toleranceen
dc.subjectinnate immunityen
dc.subjectintestine floraen
dc.subjectLactobacillalesen
dc.subjectLactobacillus rhamnosusen
dc.subjectmicrobial diversityen
dc.subjectmicrobial metabolismen
dc.subjectmicrobiomeen
dc.subjectmultiple sclerosisen
dc.subjectnerve cell plasticityen
dc.subjectnervous system developmenten
dc.subjectnonhumanen
dc.subjectProteobacteriaen
dc.subjectregulatory T lymphocyteen
dc.subjectReviewen
dc.subjectT lymphocyteen
dc.subjecttumor associated leukocyteen
dc.subjectMDPI AGen
dc.titleMicrobiome in multiple sclerosis; where are we, what we know and do not knowen
dc.typeotheren


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