Experimental Cardiac Hypertrophy Induced by Oral Administration of Mineralocorticoid and Saline in Rats

dc.creator	Voucharas, C.	en
dc.creator	Tagarakis, G.	en
dc.creator	Lazou, A.	en
dc.creator	Triposkiadis, F.	en
dc.creator	Tsilimingas, N.	en
dc.date.accessioned	2015-11-23T10:54:01Z
dc.date.available	2015-11-23T10:54:01Z
dc.date.issued	2012
dc.identifier	10.1177/0003319711423529
dc.identifier.issn	0003-3197
dc.identifier.uri	http://hdl.handle.net/11615/34629
dc.description.abstract	We suggest a new, easily applicable way of myocardial hypertrophy induction in rats. Forty randomized age-matched male Wistar rats were divided into 2 groups of 20 each: a control group and an orally administered fludrocortisone/salt group. Myocardial hypertrophy was estimated by measuring body weight, heart-weight-to-body-weight ratio and ventricular free wall thickness. Moderate myocardial hypertrophy without heart failure was established in fludrocortisone/salt group in 4 weeks. Our method is effective and low cost, and it provides a model of hypertrophic heart.	en
dc.source	Angiology	en
dc.source.uri	<Go to ISI>://WOS:000305418100004
dc.subject	heart	en
dc.subject	hypertrophy	en
dc.subject	hypertension	en
dc.subject	corticoid	en
dc.subject	fludrocortisone	en
dc.subject	rat	en
dc.subject	ADRENAL INSUFFICIENCY	en
dc.subject	HYPERTENSION	en
dc.subject	FAILURE	en
dc.subject	MODELS	en
dc.subject	ALDOSTERONE	en
dc.subject	MYOCARDIUM	en
dc.subject	DISEASE	en
dc.subject	Peripheral Vascular Disease	en
dc.title	Experimental Cardiac Hypertrophy Induced by Oral Administration of Mineralocorticoid and Saline in Rats	en
dc.type	journalArticle	en

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