dc.creator | Stefanidis, I. | en |
dc.creator | Giannopoulou, M. | en |
dc.creator | Liakopoulos, V. | en |
dc.creator | Dovas, S. | en |
dc.creator | Karasavvidou, F. | en |
dc.creator | Zachou, K. | en |
dc.creator | Koukoulis, G. K. | en |
dc.creator | Dalekos, G. N. | en |
dc.date.accessioned | 2015-11-23T10:48:46Z | |
dc.date.available | 2015-11-23T10:48:46Z | |
dc.date.issued | 2008 | |
dc.identifier.issn | 3010430 | |
dc.identifier.uri | http://hdl.handle.net/11615/33416 | |
dc.description.abstract | Sjögren syndrome (SS) is a chronic systemic autoimmune disease characterized by lymphocytic infiltration of exocrine glands, especially lacrimal and salivary. The immunologic process which occurs in this syndrome is B cell hyperactivity, which results in production of autoantibodies and immune complexes. SS can exist as a primary disorder or in association with other autoimmune processes. A usually mild, proximal and insidious inflammatory myopathy can occur in patients with SS with a broad clinical and pathological spectrum. Interstitial nephritis with mild proteinuria and tubular dysfunction is the most common renal manifestation of SS, but glomerular involvement due to immune complex deposition may also rarely occur [Goules et al. 2000]. There is an association of SS with hepatic abnormalities, as evidenced by abnormal liver biochemical tests or histological characteristics of primary biliary cirrhosis (PBC), portal tract fibrosis, or autoimmune hepatitis [Abraham et al. 2004]. The pathogenetic mechanism of liver involvement in SS is not clear, but it is possible that hepatic and salivary gland damage share a similar pathology. The combination of Sjögren syndrome with kidney, liver and muscle involvement in one entity is extremely rare and data in the literature are remarkably sparse. We present a case of a 43-year-old female patient suffering from SS accompanied by polymyositis, membranous nephropathy and autoimmune hepatitis. ©2008 Dustri-Verlag Dr. K. Feistle. | en |
dc.source.uri | http://www.scopus.com/inward/record.url?eid=2-s2.0-52149090987&partnerID=40&md5=cf226d92d176111fa4207d0ce2ffd47f | |
dc.subject | Autoimmune hepatitis | en |
dc.subject | Membranous nephropathy | en |
dc.subject | Sjögren syndrome | en |
dc.subject | alanine aminotransferase | en |
dc.subject | albumin | en |
dc.subject | antinuclear antibody | en |
dc.subject | aspartate aminotransferase | en |
dc.subject | autoantibody | en |
dc.subject | calcium | en |
dc.subject | cholesterol | en |
dc.subject | creatine kinase | en |
dc.subject | cyclophosphamide | en |
dc.subject | cyclosporin | en |
dc.subject | enoxaparin | en |
dc.subject | estrogen | en |
dc.subject | immunoglobulin A | en |
dc.subject | immunoglobulin G | en |
dc.subject | immunoglobulin M | en |
dc.subject | irbesartan | en |
dc.subject | methylprednisolone | en |
dc.subject | mycophenolic acid 2 morpholinoethyl ester | en |
dc.subject | perindopril | en |
dc.subject | prednisolone | en |
dc.subject | progesterone | en |
dc.subject | ribonucleoprotein antibody | en |
dc.subject | Ro antibody | en |
dc.subject | simvastatin | en |
dc.subject | triacylglycerol | en |
dc.subject | vitamin | en |
dc.subject | adult | en |
dc.subject | alanine aminotransferase blood level | en |
dc.subject | anemia | en |
dc.subject | ankle edema | en |
dc.subject | antibody production | en |
dc.subject | antibody titer | en |
dc.subject | antigen antibody complex | en |
dc.subject | article | en |
dc.subject | aspartate aminotransferase blood level | en |
dc.subject | autoimmune disease | en |
dc.subject | autoimmunity | en |
dc.subject | B lymphocyte | en |
dc.subject | case report | en |
dc.subject | clinical feature | en |
dc.subject | comorbidity | en |
dc.subject | diet supplementation | en |
dc.subject | disease association | en |
dc.subject | drug dose reduction | en |
dc.subject | drug substitution | en |
dc.subject | drug withdrawal | en |
dc.subject | erythrocyte sedimentation rate | en |
dc.subject | exocrine gland | en |
dc.subject | female | en |
dc.subject | hematocrit | en |
dc.subject | histopathology | en |
dc.subject | hospital admission | en |
dc.subject | human | en |
dc.subject | hypercholesterolemia | en |
dc.subject | hypergammaglobulinemia | en |
dc.subject | hypertriglyceridemia | en |
dc.subject | hypoalbuminemia | en |
dc.subject | immune complex deposition | en |
dc.subject | interstitial nephritis | en |
dc.subject | kidney biopsy | en |
dc.subject | lacrimal gland | en |
dc.subject | liver biopsy | en |
dc.subject | liver fibrosis | en |
dc.subject | liver function test | en |
dc.subject | lymphocytic infiltration | en |
dc.subject | membranous glomerulonephritis | en |
dc.subject | muscle biopsy | en |
dc.subject | muscle weakness | en |
dc.subject | myopathy | en |
dc.subject | pathophysiology | en |
dc.subject | physical examination | en |
dc.subject | polymyositis | en |
dc.subject | primary biliary cirrhosis | en |
dc.subject | proteinuria | en |
dc.subject | remission | en |
dc.subject | salivary gland | en |
dc.subject | side effect | en |
dc.subject | Sjoegren syndrome | en |
dc.subject | skin biopsy | en |
dc.subject | treatment outcome | en |
dc.subject | tubular dysfunction | en |
dc.subject | urinalysis | en |
dc.subject | Glomerulonephritis, Membranous | en |
dc.subject | Hepatitis, Autoimmune | en |
dc.subject | Humans | en |
dc.subject | Sjogren's Syndrome | en |
dc.title | A case of membranous nephropathy associated with Sjögren syndrome, polymyositis and autoimmune hepatitis | en |
dc.type | journalArticle | en |