Novel variant (bla(VlM-4)) of the metallo-beta-lactamase gene bla(VIM-1) in a clinical strain of Pseudomonas aeruginosa

dc.creator	Pournaras, S.	en
dc.creator	Tsakris, A.	en
dc.creator	Maniati, M.	en
dc.creator	Tzouvelekis, L. S.	en
dc.creator	Maniatis, A. N.	en
dc.date.accessioned	2015-11-23T10:46:06Z
dc.date.available	2015-11-23T10:46:06Z
dc.date.issued	2002
dc.identifier	10.1128/aac.46.12.4026-4028.2002
dc.identifier.issn	0066-4804
dc.identifier.uri	http://hdl.handle.net/11615/32477
dc.description.abstract	A Pseudomonas aeruginosa isolate highly resistant to carbapenems was collected from a patient with post-surgical cerebrospinal infection in Greece. The isolate carried a class I integron that contained as a sole cassette the gene bla(VIM-4), a novel variant of bla(VIM-1), with one nucleotide difference resulting in a Ser-to-Arg change at amino acid position 175 of the VIM-1 enzyme. This is the first detection of a VIM-1 variant after its appearance in Italy.	en
dc.source	Antimicrobial Agents and Chemotherapy	en
dc.source.uri	<Go to ISI>://WOS:000179376000055
dc.subject	VIM-2	en
dc.subject	RESISTANCE	en
dc.subject	INTEGRONS	en
dc.subject	ISOLATE	en
dc.subject	OUTBREAK	en
dc.subject	GREECE	en
dc.subject	BORNE	en
dc.subject	Microbiology	en
dc.subject	Pharmacology & Pharmacy	en
dc.title	Novel variant (bla(VlM-4)) of the metallo-beta-lactamase gene bla(VIM-1) in a clinical strain of Pseudomonas aeruginosa	en
dc.type	journalArticle	en

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