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Linezolid Dependence in Staphylococcus epidermidis Bloodstream Isolates

dc.creatorPournaras, S.en
dc.creatorNtokou, E.en
dc.creatorZarkotou, O.en
dc.creatorRanellou, K.en
dc.creatorThemeli-Digalaki, K.en
dc.creatorStathopoulos, C.en
dc.creatorTsakris, A.en
dc.date.accessioned2015-11-23T10:46:05Z
dc.date.available2015-11-23T10:46:05Z
dc.date.issued2013
dc.identifier10.3201/eid1901.111527
dc.identifier.issn1080-6040
dc.identifier.urihttp://hdl.handle.net/11615/32470
dc.description.abstractWe document linezolid dependence among 5 highly linezolid-resistant (LRSE) Staphylococcus epidermidis bloodstream isolates that grew substantially faster at 32 mu g/mL linezolid presence. These isolates carried the mutations T2504A and C2534T in multiple 23S rRNA copies and 2 mutations leading to relevant amino acid substitutions in L3 protein. Linezolid dependence could account for increasing LRSE emergence.en
dc.source.uri<Go to ISI>://WOS:000328172800020
dc.subjectAUREUSen
dc.subjectVANCOMYCINen
dc.subjectEMERGENCEen
dc.subjectSTRAINen
dc.subjectImmunologyen
dc.subjectInfectious Diseasesen
dc.titleLinezolid Dependence in Staphylococcus epidermidis Bloodstream Isolatesen
dc.typejournalArticleen


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