Linezolid Dependence in Staphylococcus epidermidis Bloodstream Isolates

dc.creator	Pournaras, S.	en
dc.creator	Ntokou, E.	en
dc.creator	Zarkotou, O.	en
dc.creator	Ranellou, K.	en
dc.creator	Themeli-Digalaki, K.	en
dc.creator	Stathopoulos, C.	en
dc.creator	Tsakris, A.	en
dc.date.accessioned	2015-11-23T10:46:05Z
dc.date.available	2015-11-23T10:46:05Z
dc.date.issued	2013
dc.identifier	10.3201/eid1901.111527
dc.identifier.issn	1080-6040
dc.identifier.uri	http://hdl.handle.net/11615/32470
dc.description.abstract	We document linezolid dependence among 5 highly linezolid-resistant (LRSE) Staphylococcus epidermidis bloodstream isolates that grew substantially faster at 32 mu g/mL linezolid presence. These isolates carried the mutations T2504A and C2534T in multiple 23S rRNA copies and 2 mutations leading to relevant amino acid substitutions in L3 protein. Linezolid dependence could account for increasing LRSE emergence.	en
dc.source.uri	<Go to ISI>://WOS:000328172800020
dc.subject	AUREUS	en
dc.subject	VANCOMYCIN	en
dc.subject	EMERGENCE	en
dc.subject	STRAIN	en
dc.subject	Immunology	en
dc.subject	Infectious Diseases	en
dc.title	Linezolid Dependence in Staphylococcus epidermidis Bloodstream Isolates	en
dc.type	journalArticle	en

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