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dc.creatorPolitis, A. K.en
dc.creatorStavropoulos, G. P.en
dc.creatorChristolis, M. N.en
dc.creatorPanagopoulos, F. G.en
dc.creatorVlachos, N. S.en
dc.creatorMarkatos, N. C.en
dc.date.accessioned2015-11-23T10:45:50Z
dc.date.available2015-11-23T10:45:50Z
dc.date.issued2007
dc.identifier10.1016/j.jbiomech.2006.05.008
dc.identifier.issn0021-9290
dc.identifier.urihttp://hdl.handle.net/11615/32359
dc.description.abstractThis paper presents a comparative study of simulated blood flow in different configurations of simplified composite arterial coronary grafts (CACGs). Even though the composite arterial grafting is increasingly used in cardiac surgery, it is still questionable whether or not the blood flow in such grafts can adequately meet the demands of the native myocardial circulation. A computational fluid dynamics (CFD) model was developed to conduct computer-based studies of simulated blood flow in four different geometric configurations of CACGs, corresponding to routinely used networks in cardiac surgery coronary grafts (T, Y, Pi and sequential). The flow was assumed three-dimensional, laminar and steady and the fluid as Newtonian, while the vessel walls were considered as inelastic and impermeable. It was concluded that local haemodynamics, practically described by velocity, pressure drop, wall shear stress (WSS) and flow rates, may be strongly influenced by the local geometry, especially at the anastomotic sites. The. computations were made at mean flow rates of 37.5, 75 and 150 ml/min. The side-branch outflow rates, computed for each bypass graft, showed noticeable differences. The results, which were found both qualitatively and quantitatively consistent with other studies, indicate that the Pi-graft exhibits significantly less uniform distribution of outflow rates than the other geometric configurations. Moreover, prominent variations in WSS and velocity distribution among the assessed CACGs were predicted, showing remarkable flow interactions among the arterial branches. The lowest shear stress regions were found on the lateral walls of bifurcations, which are predominantly susceptible to the occurrence of coronary artery disease (CAD). In contrast, the highest WSS were observed at the turn of the arterial branches. (c) 2006 Elsevier Ltd. All rights reserved.en
dc.source.uri<Go to ISI>://WOS:000245565400020
dc.subjectcomposite arterial coronary graftsen
dc.subjectCFDen
dc.subjectcoronary artery diseaseen
dc.subjectnumerical modellingen
dc.subjectWALL SHEAR-STRESSen
dc.subjectDYNAMIC CURVATUREen
dc.subjectBIFURCATION MODELen
dc.subjectPULSATILE FLOWen
dc.subjectHEMODYNAMICSen
dc.subjectANASTOMOSESen
dc.subjectPATTERNSen
dc.subjectGEOMETRYen
dc.subjectSTENOSISen
dc.subjectFIELDSen
dc.subjectBiophysicsen
dc.subjectEngineering, Biomedicalen
dc.titleNumerical modeling of simulated blood flow in idealized composite arterial coronary grafts: Steady state simulationsen
dc.typejournalArticleen


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