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Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases

dc.creatorKousi, E.en
dc.creatorTsougos, I.en
dc.creatorFountas, K.en
dc.creatorTheodorou, K.en
dc.creatorTsolaki, E.en
dc.creatorFezoulidis, I.en
dc.creatorKapsalaki, E.en
dc.date.accessioned2015-11-23T10:36:28Z
dc.date.available2015-11-23T10:36:28Z
dc.date.issued2012
dc.identifier10.3892/mmr.2012.773
dc.identifier.issn1791-2997
dc.identifier.urihttp://hdl.handle.net/11615/29885
dc.description.abstractThe purpose of the present study was to evaluate distinct metabolic features of meningiomas to distinguish them from other brain lesions using proton magnetic resonance spectroscopy. The study was performed on 17 meningiomas, 24 high-grade gliomas and 9 metastases. Elevated signal intensity at 3.8 ppm observed in low TE spectra adequately differentiated meningioma from other brain tumors while alanine was riot indicative of meningioma occurrence; the presence of lipids and lactate did not provide a strong index for meningioma malignancy.en
dc.sourceMolecular Medicine Reportsen
dc.source.uri<Go to ISI>://WOS:000301324100023
dc.subjectmeningiomaen
dc.subjectmagnetic resonance spectroscopyen
dc.subjectbrain lesionsen
dc.subject3-Teslaen
dc.subjectmagnetic resonance imagingen
dc.subjectMAGNETIC-RESONANCE-SPECTROSCOPYen
dc.subjectBRAIN-TUMORSen
dc.subjectINTRACRANIAL MENINGIOMASen
dc.subjectMETABOLITESen
dc.subjectOncologyen
dc.subjectMedicine, Research & Experimentalen
dc.titleDistinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastasesen
dc.typejournalArticleen


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