Isolation and characterization of a protein from Mendole (Spicara maena) eggs that binds to DNA and inhibits its replication as well as its acid precipitation

dc.creator	Kouretas, D.	en
dc.creator	Mamuris, Z.	en
dc.creator	Stamatis, C.	en
dc.creator	Rodriguez-Burgos, A.	en
dc.creator	Tsamis, V.	en
dc.creator	Neofitou, C.	en
dc.date.accessioned	2015-11-23T10:36:17Z
dc.date.available	2015-11-23T10:36:17Z
dc.date.issued	2001
dc.identifier.issn	0258-851X
dc.identifier.uri	http://hdl.handle.net/11615/29845
dc.description.abstract	Proteins that bind and protect nucleic acids from acid precipitation have been characterized from human and mouse plasma. In the present study one protein from Mendole (Spicara maena) eggs was purified to homogeneity, by means of acetone fractionation and Sephadex G-100 gel filtration. The protein inhibited DNA replication, exerted by various DNA polymerases. Amino- acid sequence analysis in the amino terminus revealed a unique sequence. Its possible physiological role is discussed.	en
dc.source.uri	<Go to ISI>://WOS:000167690700009
dc.subject	fetoprotein	en
dc.subject	DNA amplification	en
dc.subject	DNA replication	en
dc.subject	DNA binding protein	en
dc.subject	fish egg	en
dc.subject	PROTECTIVE ACTIVITY	en
dc.subject	ALPHA-FETOPROTEIN	en
dc.subject	SEQUENCES	en
dc.subject	POLY(U)	en
dc.subject	SERUM	en
dc.subject	RNA	en
dc.subject	RAT	en
dc.subject	Medicine, Research & Experimental	en
dc.title	Isolation and characterization of a protein from Mendole (Spicara maena) eggs that binds to DNA and inhibits its replication as well as its acid precipitation	en
dc.type	journalArticle	en

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