CTX-M-1 extended-spectrum beta-lactamase-producing Proteus mirabilis in Greece
dc.creator | Karapavlidou, P. | en |
dc.creator | Sofianou, D. | en |
dc.creator | Manolis, E. N. | en |
dc.creator | Pournaras, S. | en |
dc.creator | Tsakris, A. | en |
dc.date.accessioned | 2015-11-23T10:33:28Z | |
dc.date.available | 2015-11-23T10:33:28Z | |
dc.date.issued | 2005 | |
dc.identifier | 10.1089/mdr.2005.11.351 | |
dc.identifier.issn | 1076-6294 | |
dc.identifier.uri | http://hdl.handle.net/11615/29083 | |
dc.description.abstract | To examine the dissemination of CTX-M-type extended-spectrum beta-lactamases (ESBLs) in clinical isolates of Proteus mirabilis, 91 nonrepetitive ESBL-producing P. mirabilis were collected from infected patients in a tertiary Greek hospital during September, 2001, to May, 2004. A bla(CTX.M) gene was amplified in one isolate (strain A328), but bla(CTX-M) was not detected in any of the remaining ESBL producers. Sequencing results showed that P. mirabilis A328 produced a CTX-M-1 enzyme while PCR mapping of the genetic element carrying bla(CTX-M-1) revealed that the gene was located downstream of an ISEcp1B element. The cefotaxime resistance determinant was easily transferable and carried on a 70-kb plasmid. The emergence of CTX-M-1 producing P. mirabilis indicates the need for early recognition of such strains to be able to control their spread in our hospital and community environment. | en |
dc.source.uri | <Go to ISI>://WOS:000234463700006 | |
dc.subject | CTX-M ENZYMES | en |
dc.subject | ESCHERICHIA-COLI | en |
dc.subject | SALMONELLA-TYPHIMURIUM | en |
dc.subject | KLEBSIELLA-PNEUMONIAE | en |
dc.subject | HOSPITALS | en |
dc.subject | RESISTANT | en |
dc.subject | Infectious Diseases | en |
dc.subject | Microbiology | en |
dc.subject | Pharmacology & Pharmacy | en |
dc.title | CTX-M-1 extended-spectrum beta-lactamase-producing Proteus mirabilis in Greece | en |
dc.type | journalArticle | en |
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