Όλο το DSpace

Εμφάνιση απλής εγγραφής

Cytokines and pathological sleep

dc.creatorKapsimalis, F.en
dc.creatorBasta, M.en
dc.creatorVarouchakis, G.en
dc.creatorGourgoulianis, K.en
dc.creatorVgontzas, A.en
dc.creatorKryger, M.en
dc.date.accessioned2015-11-23T10:32:40Z
dc.date.available2015-11-23T10:32:40Z
dc.date.issued2008
dc.identifier10.1016/j.sleep.2007.08.019
dc.identifier.issn13899457
dc.identifier.urihttp://hdl.handle.net/11615/28900
dc.description.abstractCytokines are proteins produced by leukocytes and other cells that function as intercellular mediators acting on several target tissues, resulting in multiple biologic actions. Over the last decade, medical research has explored the interaction between cytokines and sleep disorders. The aim of this review is to illustrate recent advances in knowledge about the relationship between cytokines and disorders of excessive sleepiness. Cytokines may have an important role in mediating excessive daytime sleepiness in sleep loss or insomnia. Alterations of the immune system have also been associated with narcolepsy. The relationship between cytokines and hormonal regulatory mechanisms may explain symptoms like fatigue and sleepiness in chronic inflammatory diseases. Cytokines may play an important role in the pathogenesis of obstructive sleep apnea and cardiovascular consequences of this condition. New biologic treatments targeting cytokines have been investigated in conditions characterized by sleep disturbance. © 2007 Elsevier B.V. All rights reserved.en
dc.source.urihttp://www.scopus.com/inward/record.url?eid=2-s2.0-48449086888&partnerID=40&md5=0c7b83d78c12d6672293e0fb9d1ceb89
dc.subjectCytokinesen
dc.subjectExcessive daytime sleepinessen
dc.subjectInflammationen
dc.subjectInsomniaen
dc.subjectInsulin resistanceen
dc.subjectNarcolepsyen
dc.subjectSleep apneaen
dc.subjectSleep deprivationen
dc.subjectadiponectinen
dc.subjectC reactive proteinen
dc.subjectcorticotropinen
dc.subjectcytokineen
dc.subjectetanercepten
dc.subjectghrelinen
dc.subjectgrowth hormoneen
dc.subjectgrowth hormone releasing factoren
dc.subjectHLA antigen class 2en
dc.subjectHLA DR2 antigenen
dc.subjecthydrocortisoneen
dc.subjectimmunoglobulin enhancer binding proteinen
dc.subjectinducible nitric oxide synthaseen
dc.subjectinfliximaben
dc.subjectintercellular adhesion molecule 1en
dc.subjectinterleukin 1en
dc.subjectinterleukin 10en
dc.subjectinterleukin 1betaen
dc.subjectinterleukin 2en
dc.subjectinterleukin 6en
dc.subjectleptinen
dc.subjectneuronal nitric oxide synthaseen
dc.subjectresistinen
dc.subjecttransforming growth factor betaen
dc.subjecttumor necrosis factor alphaen
dc.subjecttumor necrosis factor receptoren
dc.subjectvasculotropinen
dc.subjectanorexiaen
dc.subjectcancer immunotherapyen
dc.subjectcardiovascular diseaseen
dc.subjectcardiovascular risken
dc.subjectcytokine productionen
dc.subjectcytokine releaseen
dc.subjectdaytime somnolenceen
dc.subjectdepressionen
dc.subjectdrug efficacyen
dc.subjectdrug induced headacheen
dc.subjecthead and neck surgeryen
dc.subjecthumanen
dc.subjectmyalgiaen
dc.subjectneoplasmen
dc.subjectneuroendocrine systemen
dc.subjectnonhumanen
dc.subjectobesityen
dc.subjectpathogenesisen
dc.subjectpositive end expiratory pressureen
dc.subjectpriority journalen
dc.subjectprotein expressionen
dc.subjectprotein functionen
dc.subjectreviewen
dc.subjectsignal transductionen
dc.subjectsleep apnea syndromeen
dc.subjectsleep disorderen
dc.subjectsleep waking cycleen
dc.subjectsomnolenceen
dc.subjecttherapy effecten
dc.subjectCardiovascular Diseasesen
dc.subjectDisorders of Excessive Somnolenceen
dc.subjectHumansen
dc.subjectRisk Factorsen
dc.titleCytokines and pathological sleepen
dc.typejournalArticleen


Αρχεία σε αυτό το τεκμήριο

ΑρχείαΜέγεθοςΤύποςΠροβολή

Δεν υπάρχουν αρχεία που να σχετίζονται με αυτό το τεκμήριο.

Αυτό το τεκμήριο εμφανίζεται στις ακόλουθες συλλογές

Εμφάνιση απλής εγγραφής