dc.creator | Jamurtas, A. Z. | en |
dc.creator | Goldfarb, A. H. | en |
dc.creator | Chung, S. C. | en |
dc.creator | Hegde, S. | en |
dc.creator | Marino, C. | en |
dc.creator | Fatouros, I. G. | en |
dc.date.accessioned | 2015-11-23T10:30:34Z | |
dc.date.available | 2015-11-23T10:30:34Z | |
dc.date.issued | 2001 | |
dc.identifier | 10.1080/026404101317108435 | |
dc.identifier.issn | 0264-0414 | |
dc.identifier.uri | http://hdl.handle.net/11615/28646 | |
dc.description.abstract | The aim of this study was to determine whether beta -endorphin infusion influences liver or muscle glycogen concentration during exercise. Thirty-two rats (Harlan Co., IN, USA) with a body mass of 265-290 g were assigned at random to four groups, each of eight rats: (1) beta -endorphin infusion for 90 min at rest; (2) beta -endorphin infusion for 90 min while running on a rodent treadmill at 22 m.min(-1) and 0% grade; (3) saline infusion (0.9% NaCl) for 90 min at rest; and (4) saline infusion for 90 min while running on a rodent treadmill at 22 m.min(-1) and 0% grade. Beta-endorphin infusion elevated plasma beta -endorphin concentration by 2.5-fold at rest compared with saline infusion at rest, and by two-fold after exercise compared with saline infusion after exercise. Beta-endorphin infusion attenuated exercise-induced glucose concentration but did not alter the fasting hepatic glycogen concentration at rest or after exercise compared with saline infusion. Fasting hepatic glycogen decreased significantly as a result of 90 min of exercise independent of treatment. Deep intermedius muscle glycogen concentration at rest was similar after 90 min of both beta -endorphin and saline infusion and decreased significantly as a result of 90 min of exercise independent of treatment. Our results suggest that liver and muscle glycogenolysis is not responsible for the differences in plasma glucose with beta -endorphin infusion during exercise. | en |
dc.source | Journal of Sports Sciences | en |
dc.source.uri | <Go to ISI>://WOS:000172420800004 | |
dc.subject | glucagon | en |
dc.subject | gluconeogenesis | en |
dc.subject | glucose | en |
dc.subject | opioid | en |
dc.subject | HIGH-INTENSITY EXERCISE | en |
dc.subject | GLUCOSE-HOMEOSTASIS | en |
dc.subject | ENDOGENOUS OPIOIDS | en |
dc.subject | GLUCAGON | en |
dc.subject | SECRETION | en |
dc.subject | PEPTIDES | en |
dc.subject | INSULIN | en |
dc.subject | GLUCONEOGENESIS | en |
dc.subject | MECHANISMS | en |
dc.subject | METABOLISM | en |
dc.subject | Sport Sciences | en |
dc.title | Beta-endorphin infusion during exercise in rats does not alter hepatic or muscle glycogen | en |
dc.type | journalArticle | en |