Hidden VIM-1 metallo-beta-lactamase phenotypes among Acinetobacter baumannii clinical isolates

dc.creator	Ikonornidis, A.	en
dc.creator	Ntokou, E.	en
dc.creator	Maniatis, A. N.	en
dc.creator	Tsakris, A.	en
dc.creator	Pournaras, S.	en
dc.date.accessioned	2015-11-23T10:30:20Z
dc.date.available	2015-11-23T10:30:20Z
dc.date.issued	2008
dc.identifier	10.1128/jcm.01670-07
dc.identifier.issn	0095-1137
dc.identifier.uri	http://hdl.handle.net/11615/28569
dc.description.abstract	A total of 87 Acinetobacter baumannii nonrepetitive consecutive clinical isolates were tested for the presence of metallo-beta-lactamases (MBLs). Results of phenotypic assays (MBL Etest, imipenem/imipenem-EDTA combined-disk test, and imipenem/EDTA double-disk synergy test) were negative in all cases, but molecular testing revealed the presence of two bla(VIM-1)-carrying isolates. One isolate had bla(VIM-1) preceded by a weak P1 promoter, and both had inactivated P2 promoters and reduced bla(VIM-1), expression, partially justifying the results revealing hidden MBL phenotypes.	en
dc.source	Journal of Clinical Microbiology	en
dc.source.uri	<Go to ISI>://WOS:000252392200051
dc.subject	PSEUDOMONAS-AERUGINOSA	en
dc.subject	GENE	en
dc.subject	IDENTIFICATION	en
dc.subject	CARBAPENEMASE	en
dc.subject	RESISTANCE	en
dc.subject	INTEGRON	en
dc.subject	Microbiology	en
dc.title	Hidden VIM-1 metallo-beta-lactamase phenotypes among Acinetobacter baumannii clinical isolates	en
dc.type	journalArticle	en

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