New short route to unsaturated fluoroketonucleosides: Case of 5-fluoro-1-(6-0-acetyl-3,4-di-deoxy-3-fluoro-β-D-glycero-hex-3-eno-pyranos- 2-ulosyl) uracil
dc.creator | Egron, M. J. | en |
dc.creator | Komiotis, D. | en |
dc.creator | Dorange, I. | en |
dc.creator | Herscovici, J. | en |
dc.creator | Ollapally, A. P. | en |
dc.creator | Antonakis, K. | en |
dc.date.accessioned | 2015-11-23T10:26:05Z | |
dc.date.available | 2015-11-23T10:26:05Z | |
dc.date.issued | 2005 | |
dc.identifier | 10.1081/NCN-59683 | |
dc.identifier.issn | 15257770 | |
dc.identifier.uri | http://hdl.handle.net/11615/27295 | |
dc.description.abstract | The proposed short synthesis involves two key steps: Oxidation of the isopropylidene derivative of the 3-fluoronucleoside possessing a free hydroxyl group in 2-position and acetylation of deprotected 3-fluoro-2-ketonucleoside which, after a β-elimination reaction, gives the desired unsaturated ketonucleoside 5. Copyright © Taylor & Francis, Inc. | en |
dc.source.uri | http://www.scopus.com/inward/record.url?eid=2-s2.0-22044448379&partnerID=40&md5=ac121ffefe37f698b8c090964e707674 | |
dc.subject | 5 fluoro 1 (6 o acetyl 3,4 dideoxy 3 fluoro beta dextro glycerohex 3 enopyranos 2 ulosyl)uracil | en |
dc.subject | acetic acid derivative | en |
dc.subject | fluorine derivative | en |
dc.subject | hydroxyl group | en |
dc.subject | ketone derivative | en |
dc.subject | nucleoside derivative | en |
dc.subject | unclassified drug | en |
dc.subject | uracil derivative | en |
dc.subject | acetylation | en |
dc.subject | article | en |
dc.subject | deprotection reaction | en |
dc.subject | drug synthesis | en |
dc.subject | elimination reaction | en |
dc.subject | oxidation | en |
dc.subject | reaction analysis | en |
dc.subject | Chromatography, Thin Layer | en |
dc.subject | Fluorine | en |
dc.subject | Fluorouracil | en |
dc.subject | Immunosuppressive Agents | en |
dc.subject | Ketones | en |
dc.subject | Magnetic Resonance Spectroscopy | en |
dc.subject | Models, Chemical | en |
dc.subject | Nucleosides | en |
dc.subject | Uracil | en |
dc.title | New short route to unsaturated fluoroketonucleosides: Case of 5-fluoro-1-(6-0-acetyl-3,4-di-deoxy-3-fluoro-β-D-glycero-hex-3-eno-pyranos- 2-ulosyl) uracil | en |
dc.type | journalArticle | en |
Αρχεία σε αυτό το τεκμήριο
Αρχεία | Μέγεθος | Τύπος | Προβολή |
---|---|---|---|
Δεν υπάρχουν αρχεία που να σχετίζονται με αυτό το τεκμήριο. |