dc.creator | Chini, V. | en |
dc.creator | Petinaki, E. | en |
dc.creator | Foka, A. | en |
dc.creator | Paratiras, S. | en |
dc.creator | Dimitracopoulos, G. | en |
dc.creator | Spiliopoulou, I. | en |
dc.date.accessioned | 2015-11-23T10:24:37Z | |
dc.date.available | 2015-11-23T10:24:37Z | |
dc.date.issued | 2006 | |
dc.identifier.issn | 1198-743X | |
dc.identifier.uri | http://hdl.handle.net/11615/26636 | |
dc.description.abstract | Three collections of Staphylococcus aureus isolates (n = 1058) were investigated to assess the spread of Panton-Valentine leukocidin (PVL)-producing strains in Greece and their association with skin and soft-tissue :infections (SSTIs). The isolates were collected during 2001-2003 from inpatients and outpatients with invasive infections in two distinct geographical areas. Clonal types were identified according to their ClaI-mecA::ClaI-Tn554::pulsed-field gel electrophoresis patterns, and the presence of the lukS-PV and lukF-PV genes was assessed by PCR. In total, 287 (27%) S. aureus isolates carried the PVL genes: 45% of methicillin-resistant S. aureus (MRSA) and 12% of methicillin-sensitive S. aureus (MSSA). All the PVL-positive MRSA isolates belonged to a single clone that was disseminated in the community and hospitals. The PVL-positive MSSA isolates were polyclonal, with 14 of 65 isolates being associated with hospital-acquired infections. The community-acquired isolates were from SSTIs, while the hospital-acquired isolates were associated with surgical wound infections, especially those involving prosthetic devices. Thus, a unique clone of PVL-positive MRSA has spread in both the community and the hospital setting in Greece, and has replaced older clonal types. | en |
dc.source | Clinical Microbiology and Infection | en |
dc.source.uri | <Go to ISI>://WOS:000234512800005 | |
dc.subject | clones | en |
dc.subject | Greece | en |
dc.subject | MRSA | en |
dc.subject | Panton-Valentine leukocidin | en |
dc.subject | skin and soft-tissue | en |
dc.subject | infections | en |
dc.subject | Staphylococcus aureus | en |
dc.subject | METHICILLIN-RESISTANT | en |
dc.subject | COMMUNITY | en |
dc.subject | INFECTIONS | en |
dc.subject | PNEUMONIA | en |
dc.subject | EMERGENCE | en |
dc.subject | DISEASE | en |
dc.subject | CLONES | en |
dc.subject | SKIN | en |
dc.subject | Infectious Diseases | en |
dc.subject | Microbiology | en |
dc.title | Spread of Staphylococcus aureus clinical isolates carrying Panton-Valentine leukocidin genes during a 3-year period in Greece. | en |
dc.type | journalArticle | en |